Doxicline 100 mg (Capsule)

Unit Price: ৳ 2.00 (10 x 10: ৳ 200.00)
Strip Price: ৳ 20.00

Medicine Details

Category Details
Generic Doxycycline hydrochloride
Company Ziska pharmaceuticals ltd

Indications

  • Respiratory tract infections:
    • pneumonia
    • influenza
    • sinusitis
    • bronchitis
    • tonsillitis
    • tracheitis
  • Gastrointestinal tract infections:
    • cholera
    • traveler's diarrhea
    • shigella dysentery
    • acute intestinal amebiasis
  • Chlamydial infections:
    • lympho-granuloma venereum
    • psittacosis
    • trachoma
  • Sexually transmitted diseases:
    • non gonococcal urethritis
    • acute pelvic inflammatory disease
    • gonorrhea
    • syphilis
  • Other infections:
    • impetigo
    • furunculosis
    • inclusion conjunctivitis
    • brucellosis
    • tularemia
    • cellulitis
    • acne
    • Q-fever

Description

Highly active broad-spectrum antibiotic of tetracycline group effective against a wide range of Gram-positive and Gram-negative bacteria, spirochete, mycoplasma, rickettsia, and mycobacteria.

Pharmacology

  • Spectrum of activity:
    • Gram-positive bacteria
    • Gram-negative bacteria
    • spirochetes
    • mycoplasma
    • rickettsiae
    • mycobacteria
    • Staphylococcus aureus
    • Nocardia
    • E. coli
    • Proteus mirabilis
    • Klebsiella
    • penicillin-resistant strains
    • anaerobes
    • Haemophilus influenzae
    • H. ducreyi
    • Actinomyces
    • Brucella
    • Vibrio cholerae
    • Nocardia
    • Chlamydia
    • Plasmodium falciparum

Dosage

  • Usual dose: 200 mg on first day, then 100 mg daily for 7-10 days
  • Severe infections: 200 mg daily for 10 days
  • Acne: 100 mg daily
  • Genital chlamydia, non-gonococcal urethritis: 100 mg twice daily for 7-21 days

Administration

Capsules should be swallowed whole with plenty of fluid during meals while sitting or standing.

Interaction

  • Impairment of absorption by:
    • antacids containing aluminium, calcium, or magnesium
    • iron-containing preparations
    • bismuth salicylate
  • Medications reducing half-life:
    • barbiturates
    • carbamazepine
    • phenytoin
  • Concurrent use effects: render oral contraceptives less effective
  • Anticoagulant therapy: may require downward adjustment of dosages
  • Advice: Avoid giving tetracyclines in conjunction with penicillin

Contraindications

  • Hypersensitivity to any tetracyclines
  • Children under 8 years of age
  • Pregnant women
  • Lactating mothers

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Skin rashes
  • Hemolytic anemia
  • Eosinophilia

Pregnancy & Lactation

  • Pregnancy: Avoided due to risk of staining and effect on bone growth in the fetus
  • Lactation: Mothers taking these drugs should not breastfeed their child

Precautions & Warnings

Avoid use during tooth development (last half of pregnancy, infancy and childhood to the age of 8 years) to prevent permanent discoloration of teeth.

Therapeutic Class

Tetracycline group of drugs

Storage Conditions

Keep all medicines out of reach of children. Store in a cool and dry place, protected from light

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