Tydox 100 mg (Capsule)

Unit Price: ৳ 2.01 (10 x 10: ৳ 201.00)
Strip Price: ৳ 20.10

Medicine Details

Title

  • Tydox

Categories

  • Antibiotic
  • Medication
  • Pharmaceutical

Description

  • Highly active broad-spectrum antibiotic
  • Effective against Gram-positive and Gram-negative bacteria
  • Effective against spirochete, mycoplasma, rickettsia, and mycobacteria
  • Used as an alternate to penicillin in the treatment of gonorrhea and syphilis
  • Main mechanism of action on protein synthesis

Indications

  • Treatment of respiratory tract infections such as pneumonia, influenza, sinusitis, bronchitis, tonsillitis, and tracheitis
  • Treatment of gastrointestinal tract infections including cholera, traveler's diarrhea, shigella dysentery, and acute intestinal amebiasis
  • Treatment of chlamydial infections like lympho-granuloma venereum, psittacosis, and trachoma
  • Treatment of sexually transmitted diseases like non-gonococcal urethritis, acute pelvic inflammatory disease, and gonorrhea
  • Treatment of other infections such as impetigo, furunculosis, and conjunctivitis

Pharmacology

  • Semisynthetic tetracycline antibiotic with broad spectrum activity
  • Primarily a bacteriostatic antibiotic
  • More active against Staphylococcus aureus and Nocardia
  • Active against penicillin-resistant strains of Staphylococcus aureus
  • Active against certain Gram-negative strains of E. coli, Proteus mirabilis, and Klebsiella
  • Active against Haemophilus influenzae and H. ducreyi
  • Active against Actinomyces, Brucella, Vibrio cholerae, Nocardia, Chlamydia, Mycoplasma, and a wide range of Rickettsiae
  • Active against spirochetes such as Borellia recurrentis, Treponema pallidum, and Treponema pertenue
  • Active against Plasmodium falciparum

Dosage

  • Usual dose: 200 mg on first day, then 100 mg daily for 7-10 days
  • Severe infections: 200 mg daily for 10 days
  • Acne: 100 mg daily
  • Uncomplicated genital chlamydia, non-gonococcal urethritis: 100 mg twice daily for 7-21 days

Administration

  • Capsules should be swallowed whole with plenty of fluid during meals while sitting or standing

Interaction

  • Absorption of tetracyclines is impaired by antacids containing aluminum, calcium, or magnesium, and iron-containing preparations
  • Absorption of tetracyclines is impaired by bismuth salicylate
  • Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline
  • Concurrent use of tetracyclines may render oral contraceptives less effective
  • Patients on anticoagulant therapy may require downward adjustment of their anticoagulant dosages
  • Tetracyclines should be avoided in conjunction with penicillin

Contraindications

  • Hypersensitivity to any of the tetracyclines
  • Children under 8 years of age
  • Pregnant women
  • Lactating mothers

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Skin rashes
  • Hemolytic anemia
  • Eosinophilia

Pregnancy & Lactation

  • Should be avoided in pregnant women due to the risk of staining and effect on bone growth in the fetus
  • Enters breast milk, mothers taking these drugs should not breastfeed their child

Precautions & Warnings

  • Tetracyclines may cause permanent discoloration of teeth if used during tooth development (last half of pregnancy, infancy, and childhood to the age of 8 years)

Therapeutic Class

  • Tetracycline group of drugs

Storage Conditions

  • Keep all medicines out of reach of children
  • Store in a cool and dry place, protected from light

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