Tydox 100 mg (Capsule)
Unit Price: ৳ 2.01 (10 x 10: ৳ 201.00)
Strip Price: ৳ 20.10
Medicine Details
Category | Details |
---|---|
Generic | Doxycycline hydrochloride |
Company | Somatec pharmaceuticals ltd |
Title
- Tydox
Categories
- Antibiotic
- Medication
- Pharmaceutical
Description
- Highly active broad-spectrum antibiotic
- Effective against Gram-positive and Gram-negative bacteria
- Effective against spirochete, mycoplasma, rickettsia, and mycobacteria
- Used as an alternate to penicillin in the treatment of gonorrhea and syphilis
- Main mechanism of action on protein synthesis
Indications
- Treatment of respiratory tract infections such as pneumonia, influenza, sinusitis, bronchitis, tonsillitis, and tracheitis
- Treatment of gastrointestinal tract infections including cholera, traveler's diarrhea, shigella dysentery, and acute intestinal amebiasis
- Treatment of chlamydial infections like lympho-granuloma venereum, psittacosis, and trachoma
- Treatment of sexually transmitted diseases like non-gonococcal urethritis, acute pelvic inflammatory disease, and gonorrhea
- Treatment of other infections such as impetigo, furunculosis, and conjunctivitis
Pharmacology
- Semisynthetic tetracycline antibiotic with broad spectrum activity
- Primarily a bacteriostatic antibiotic
- More active against Staphylococcus aureus and Nocardia
- Active against penicillin-resistant strains of Staphylococcus aureus
- Active against certain Gram-negative strains of E. coli, Proteus mirabilis, and Klebsiella
- Active against Haemophilus influenzae and H. ducreyi
- Active against Actinomyces, Brucella, Vibrio cholerae, Nocardia, Chlamydia, Mycoplasma, and a wide range of Rickettsiae
- Active against spirochetes such as Borellia recurrentis, Treponema pallidum, and Treponema pertenue
- Active against Plasmodium falciparum
Dosage
- Usual dose: 200 mg on first day, then 100 mg daily for 7-10 days
- Severe infections: 200 mg daily for 10 days
- Acne: 100 mg daily
- Uncomplicated genital chlamydia, non-gonococcal urethritis: 100 mg twice daily for 7-21 days
Administration
- Capsules should be swallowed whole with plenty of fluid during meals while sitting or standing
Interaction
- Absorption of tetracyclines is impaired by antacids containing aluminum, calcium, or magnesium, and iron-containing preparations
- Absorption of tetracyclines is impaired by bismuth salicylate
- Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline
- Concurrent use of tetracyclines may render oral contraceptives less effective
- Patients on anticoagulant therapy may require downward adjustment of their anticoagulant dosages
- Tetracyclines should be avoided in conjunction with penicillin
Contraindications
- Hypersensitivity to any of the tetracyclines
- Children under 8 years of age
- Pregnant women
- Lactating mothers
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Skin rashes
- Hemolytic anemia
- Eosinophilia
Pregnancy & Lactation
- Should be avoided in pregnant women due to the risk of staining and effect on bone growth in the fetus
- Enters breast milk, mothers taking these drugs should not breastfeed their child
Precautions & Warnings
- Tetracyclines may cause permanent discoloration of teeth if used during tooth development (last half of pregnancy, infancy, and childhood to the age of 8 years)
Therapeutic Class
- Tetracycline group of drugs
Storage Conditions
- Keep all medicines out of reach of children
- Store in a cool and dry place, protected from light