Meroclav 250 mg+62.5 mg (Tablet)

Unit Price: ৳ 30.00 (2 x 10: ৳ 600.00)
Strip Price: ৳ 300.00

Medicine Details

Category Details
Generic Cefuroxime axetil clavulanic acid
Company Ibn sina pharmaceuticals ltd
Also available as
Meroclav 500 mg tablet Meroclav 125 mg suspension

Title

  • Meroclav 250 mg Tablet

Categories

  • Medicine
  • Antibiotic
  • Infection Treatment

Indications

  • Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
  • Acute Bacterial Otitis Media
  • Acute bacterial maxillary sinusitis
  • Lower respiratory tract infections
  • Acute bacterial exacerbation of chronic bronchitis
  • Uncomplicated skin and skin-structure infections
  • Uncomplicated urinary tract infections
  • Bone and Joint Infections
  • Uncomplicated Gonorrhoea
  • Early Lyme Disease
  • Septicemia
  • Meningitis
  • Switch therapy (Injectable to oral)

Pharmacology

  • Bactericidal second generation cephalosporin antibiotic
  • Active against a wide range of Gram-positive and Gram-negative susceptible organisms
  • Inhibits bacterial cell wall synthesis by interfering with the transpeptidation process
  • Clavulanic acid is a beta lactamase inhibitor produced by Streptomyces clavuligerus
  • Clavulanic acid protects Cefuroxime from degradation by beta lactamase enzymes

Dosage & Administration

  • 250-500 mg b.i.d. for adults
  • 20 mg/kg/day b.i.d. for paediatric patients
  • Can be taken without regard of food

Interaction

  • Concomitant administration of probenecid increases the area under the serum concentration versus time curve by 50%
  • Drug that reduces gastric acidity may result in a lower bioavailability of Cefuroxime

Contraindications

  • Known allergy to cephalosporin
  • Pseudomembranous Colitis

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort or pain
  • Prolonged administration may result in overgrowth of nonsusceptible microorganisms
  • Rarely: renal dysfunction, anaphylaxis, angioedema, pruritis, rash, urticaria

Pregnancy & Lactation

  • Should be avoided in the first trimester if possible
  • Can be safely used in later pregnancy to treat urinary and other infections
  • Excreted into the breast milk in small quantities

Precautions & Warnings

  • Given with care to patients receiving concurrent treatment with potent diuretics and with history of colitis

Therapeutic Class

  • Second generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place (below 30°C)
  • Away from light and moisture
  • Keep out of the reach of children

Common Questions

  • Used to treat infections caused by sensitive bacteria
  • Indicated for pharyngitis, tonsillitis, sinusitis, bronchitis, SSTI, UTI, gonorrhoea, pneumonia, typhoid fever
  • Starts working within 2-3 hours after taking
  • Lasts for an average duration of 4-8 hours
  • Safety with alcohol consumption is unknown
  • Not habit forming
  • Safe to consume during pregnancy and breastfeeding
  • Quick tips provided for usage

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