Vilip 50 mg (Tablet)
Unit Price: ৳ 19.00 (3 x 10: ৳ 570.00)
Strip Price: ৳ 190.00
Medicine Details
Category | Details |
---|---|
Generic | Vildagliptin |
Company | Team pharmaceuticals ltd |
Product Title
- Vilip Tablets
Categories
- Medicine
- Diabetes Management
Description
- Vilip is indicated as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus as monotherapy and in dual combination with other antidiabetic agents when diet and exercise alone do not suffice.
Dosage Options
- 50 mg or 100 mg daily for monotherapy
- 50 mg twice daily (morning and evening) when used in dual combination with Metformin or a Thiazolidinedione
- 50 mg once daily in the morning when used in dual combination with a Sulphonylurea
Pharmacological Action
- Dipeptidyl Peptidase-4 (DPP-4) inhibitor
- Slows the inactivation of incretin hormones
- Increases insulin release and decreases glucagon levels in a glucose-dependent manner
Interaction
- No interactions with pioglitazone, metformin, glibenclamide, digoxin, warfarin, amlodipine, ramipril, valsartan or simvastatin observed
- Glucose-lowering effect may be reduced by certain active substances such as thiazides, corticosteroids, thyroid products, and sympathomimetics
Contraindications
- Hypersensitivity to the active substance or excipients
- Moderate to severe renal impairment
- Hepatic impairment: patients with pre-treatment ALT or AST >3 times the upper limit of normal (ULN)
- Type 1 diabetes
Side Effects
- Majority of adverse reactions are mild and transient
- Rare cases of hepatic dysfunction reported
- No additional safety signals identified in clinical trials of up to and more than 2 years duration
Pregnancy & Lactation
- Not to be used during pregnancy
- Not to be used during lactation
Precautions & Warnings
- Caution in patients aged 75 years and older
- Monitoring of LFTs prior to initiation of Vilip and at three-monthly intervals in the first year
- Discontinue if transaminase levels are significantly increased
- Do not reinitiate treatment after withdrawal due to liver abnormalities
- Use with caution in patients with congestive heart failure of NYHA functional class I-II
- Avoid in patients with NYHA functional class III IV
Therapeutic Class
- Dipeptidyl Peptidase-4 (DPP-4) inhibitor
Storage Conditions
- Store below 30°C
- Keep away from light and moisture
- Keep out of reach of children