Carlina-M 2.5 mg+500 mg (Tablet)
Unit Price: ৳ 13.00 (4 x 6: ৳ 312.00)
Strip Price: ৳ 78.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Linagliptin metformin hydrochloride |
| Company | Radiant pharmaceuticals ltd |
Indications
- Adjunct to diet and exercise
- Improves glycemic control
- Type 2 diabetes mellitus
Pharmacology
- Inhibits DPP-4 enzyme
- Increases active incretin hormone concentrations
- Stimulates insulin release from pancreatic beta cells
- Decreases glucagon secretion from pancreatic alpha cells
- Lowers basal and postprandial plasma glucose
- Improves insulin sensitivity
Dosage & Administration
- Immediate release tablet
- Extended release tablet
- Individualized dosage
- Maximum recommended dose
- Gradual dose escalation
- Recommended starting dose
- Switching from individual components
- Once daily dosage
Interaction
- Cationic drug interaction
- Carbonic anhydrase inhibitors interaction
- Inducers of P-glycoprotein and CYP3A4 enzymes interaction
- Drugs affecting glycemic control interaction
Contraindications
- Renal impairment
- Metabolic acidosis
- Hypersensitivity to components
Side Effects
- Nasopharyngitis
- Diarrhea
- Hypoglycemia
- Sulfonylureas interaction
Pregnancy & Lactation
- Limited studies in pregnant women
- Caution during lactation
Precautions & Warnings
- Discontinue in lactic acidosis
- Discontinue in pancreatitis
- Discontinue during radiologic studies and surgical procedures
- Vitamin B12 level monitoring
- Symptoms of lactic acidosis
- Temporary cessation for major surgery or diagnostic tests
- Alcohol consumption precautions
- Monitoring for side effects
- Travel considerations
- Emergency preparedness
- Hypoglycemia precautions
Overdose Effects
- Supportive measures
- Hemodialysis for Metformin
- No dose-related clinical adverse reactions at high doses
- Hypoglycemia in Metformin overdose
- Lactic acidosis in Metformin overdose
Therapeutic Class
- Oral hypoglycemic preparations
Storage Conditions
- Cool and dry storage
- Below 30°C
- Protected from light and moisture
- Keep out of reach of children