Kinexa 15 mg (Tablet)
Unit Price: ৳ 35.00 (2 x 10: ৳ 700.00)
Strip Price: ৳ 350.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rivaroxaban |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Prevention of atherothrombotic events in adult patients after an Acute Coronary Syndrome (ACS)
- Reduction in the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation
- Treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE)
- Prophylaxis of DVT in patients undergoing knee or hip replacement surgery
Pharmacology
Highly selective direct factor Xa inhibitor
Dosage & Administration
- Recommended dose of 2.5 mg twice daily with or without food
- Different doses for nonvalvular atrial fibrillation, DVT, PE, and prophylaxis following surgery
Interaction
- Avoid concomitant use with combined P-gp and CYP3A4 inhibitors
- Avoid co-administration with combined P-gp and strong CYP3A4 inducers
- Increased risk of bleeding with concomitant use of anti-platelet agents, heparin, and NSAIDs
Contraindications
Known hypersensitivity to Rivaroxaban, active pathological bleeding
Side Effects
- Increased chance of bleeding
- Spinal or epidural hematoma
- Increased risk of stroke after discontinuation in nonvalvular atrial fibrillation
Pregnancy & Lactation
Pregnancy category C drug, inadequate studies in pregnant and breastfeeding women
Precautions & Warnings
- Increased risk of thrombotic events with early discontinuation
- Fatal risk of bleeding in the presence of certain risk factors
- Monitoring neurological impairment during neuraxial anesthesia
Overdose Effects
- May lead to hemorrhage
- Specific antidote not available
- Activated charcoal and plasma products for management
Therapeutic Class
Oral Anti-coagulants
Storage Conditions
Store below 30°C, protected from light, and out of reach of children