Kinexa 2.5 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rivaroxaban |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Prevention of atherothrombotic events in adult patients after an Acute Coronary Syndrome
- Reduction in the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation
- Treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE)
- Prophylaxis of DVT in patients undergoing knee or hip replacement surgery
Pharmacology
Rivaroxaban is a highly selective direct factor Xa inhibitor. Inhibition of factor Xa interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibits thrombin formation.
Dosage & Administration
- Recommended dosage for different conditions and patient profiles
- Instructions for intake with or without food
Interaction
Information on drugs that should be avoided when using Kinexa and their effects on exposure and pharmacodynamic effects
Contraindications
- Contraindicated in patients with known hypersensitivity to Rivaroxaban or any of the excipients
- Contraindicated in patients with active pathological bleeding
Side Effects
- Increased chance of bleeding
- Spinal or epidural hematoma
- Increased risk of stroke after discontinuation in nonvalvular atrial fibrillation
Pregnancy & Lactation
- Pregnancy category C drug
- No established dosing for pregnant women
- Unknown excretion in human milk
- Safety and efficacy not established in breastfeeding women
Precautions & Warnings
- Risk factors and conditions that may increase the risk of bleeding
- Monitoring signs or symptoms of neurological impairment
- Recommendations for patients with pulmonary embolism and hemodynamic instability
Overdose Effects
- May lead to hemorrhage
- Specific antidote not available
- Use of activated charcoal to reduce absorption
- Partial reversal of laboratory anticoagulation parameters with plasma products
Therapeutic Class
Oral Anti-coagulants
Storage Conditions
Store in a cool (below 30°C) and dry place protected from light. Keep away from the reach of children.