Kinexa 2.5 mg (Tablet)

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Indications

  • Prevention of atherothrombotic events in adult patients after an Acute Coronary Syndrome
  • Reduction in the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation
  • Treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE)
  • Prophylaxis of DVT in patients undergoing knee or hip replacement surgery

Pharmacology

Rivaroxaban is a highly selective direct factor Xa inhibitor. Inhibition of factor Xa interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibits thrombin formation.

Dosage & Administration

  • Recommended dosage for different conditions and patient profiles
  • Instructions for intake with or without food

Interaction

Information on drugs that should be avoided when using Kinexa and their effects on exposure and pharmacodynamic effects

Contraindications

  • Contraindicated in patients with known hypersensitivity to Rivaroxaban or any of the excipients
  • Contraindicated in patients with active pathological bleeding

Side Effects

  • Increased chance of bleeding
  • Spinal or epidural hematoma
  • Increased risk of stroke after discontinuation in nonvalvular atrial fibrillation

Pregnancy & Lactation

  • Pregnancy category C drug
  • No established dosing for pregnant women
  • Unknown excretion in human milk
  • Safety and efficacy not established in breastfeeding women

Precautions & Warnings

  • Risk factors and conditions that may increase the risk of bleeding
  • Monitoring signs or symptoms of neurological impairment
  • Recommendations for patients with pulmonary embolism and hemodynamic instability

Overdose Effects

  • May lead to hemorrhage
  • Specific antidote not available
  • Use of activated charcoal to reduce absorption
  • Partial reversal of laboratory anticoagulation parameters with plasma products

Therapeutic Class

Oral Anti-coagulants

Storage Conditions

Store in a cool (below 30°C) and dry place protected from light. Keep away from the reach of children.

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