Kinexa 20 mg (Tablet)
Unit Price: ৳ 45.00 (2 x 10: ৳ 900.00)
Strip Price: ৳ 450.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rivaroxaban |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Prevention of atherothrombotic events in adult patients after an Acute Coronary Syndrome (ACS)
- Reduction in the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation
- Deep vein thrombosis (DVT) and pulmonary embolism (PE) risk reduction
- Prophylaxis of DVT after knee or hip replacement surgery
Pharmacology
- Highly selective direct factor Xa inhibitor
- Inhibition of the blood coagulation cascade
- No effects on platelets
Dosage & Administration
- Recommended dose: 2.5 mg or 10-20 mg
- Twice daily administration
- Different doses for different indications
- May be taken with or without food
Interaction
- Contraindicated with combined P-gp and CYP3A4 inhibitors
- Contraindicated with P-gp and strong CYP3A4 inducers
- Potential risk of increased bleeding with certain drug co-administration
Contraindications
- Known hypersensitivity to Rivaroxaban or any excipient
- Active pathological bleeding
Side Effects
- Increased chance of bleeding
- Spinal or epidural hematoma
- Increased risk of stroke after discontinuation in nonvalvular atrial fibrillation
Pregnancy & Lactation
- Pregnancy category C drug
- No established dosing for pregnant women
- No established safety and efficacy in breastfeeding women
Precautions & Warnings
- Increased risk of thrombotic events upon early discontinuation
- Fatal bleeding risk in the presence of certain factors
- Monitoring for signs of neurological impairment during specific procedures
- Not recommended in specific patient populations
Overdose Effects
- Potential hemorrhage
- No specific antidote available
- Use of activated charcoal for overdose absorption reduction
- Partial reversal of anticoagulation parameters with plasma products
Therapeutic Class
- Oral Anticoagulants
Storage Conditions
- Store in a cool and dry place below 30°C
- Protected from light
- Keep away from the reach of children