Telmacal 5 mg+80 mg (Tablet)
Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate telmisartan |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of hypertension
- Combination therapy
- Blood pressure goals
Pharmacology
- Fixed dose combination of Telmisartan and Amiodipine
- Action on angiotensin II
- Vasoconstriction
- Stimulation of aldosterone release
- Renal reabsorption of sodium
- Selective AT1 receptor blocking
- Vasodilation
- Reduction in blood pressure
- Calcium-channel blocker
- Inhibition of calcium ion influx
Dosage & Administration
- Initial therapy dose: 40/5 mg once daily
- Alternative starting dose: 80/5 mg once daily
- Add-on therapy for inadequate blood pressure control
- Replacement therapy for individualized dosages
Interaction
- Co-administration with various drugs
- Inhibition of CYP2C19 metabolism
- Safe administration with other medications
Contraindications
- Known hypersensitivity
- Pregnancy & lactation
- Biliary obstructive disorders
- Severe hepatic impairment
- Hypotension
- Cardiogenic shock
- Left ventricle outflow tract obstruction
Side Effects
- Dizziness
- Peripheral edema
- Migraine
- Headache
- Bradycardia
- Palpitations
- Hypotension
- Cough
- Abdominal pain
- Diarrhea
- Nausea
- Pruritus
- Myalgia
- Erectile dysfunction
- Chest pain
- Fatigue
Pregnancy & Lactation
- Pregnancy Categories C and D
- Excretion in human milk
- Adverse effects on nursing infant
Precautions & Warnings
- Avoid fetal or neonatal exposure
- Correct volume or salt depletion before therapy
- Gradual titration for hepatic or severe renal impairment
- Monitoring for worsening heart failure
- Avoid concomitant ACE inhibitor and angiotensin receptor blocker use
- Risk of myocardial infarction
Use in Special Populations
- No established pediatric use
- Caution in geriatric patients
- Not recommended for hepatically impaired patients
Overdose Effects
- Manifestations of overdosage for Telmisartan
- Hypotension, dizziness, tachycardia
- Manifestations of overdosage for Amiodipine
- Excessive peripheral vasodilation
- Marked hypotension
- Reflex tachycardia
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Protect from light and high humidity
- Keep out of the reach of children