Ural-K (1500 mg+250 mg)/5 ml (Oral Solution)

Indications

• Relief of discomfort in urinary tract infections
• Prevention of kidney stones
• Prevention of gout when used with uricosuric agent
• Treatment of acidosis caused by kidney diseases

Pharmacology

• Potassium Citrate and Citric Acid oral solution
• Systemic alkalizer
• Metabolized to Potassium Bicarbonate
• Alkalinizes the urine without producing systemic alkalosis
• Highly palatable and pleasant tasting
• Does not neutralize gastric juice or disturb digestion

Dosage & Administration

• Adult dose: 10-15 ml 4 times daily
• Adults and children over 6 years: 10 ml 3 times daily
• Children 1-6 years: 5 ml 3 times daily
• Pediatric dose: 5-10 ml 4 times daily
• To be diluted with water

Interaction

• Concurrent administration of potassium-containing medication may lead to toxicity
• Concurrent administration of potassium-sparing diuretics may lead to toxicity
• Concurrent administration of ACE inhibitors may lead to toxicity
• Concurrent administration of cardiac glycosides may lead to toxicity

Contraindications

• Severe renal impairment with oliguria or azotemia
• Untreated Addison's disease
• Acute dehydration
• Severe myocardial damage
• Hyperkalemia from any cause

Side Effects

• Well tolerated in patients with normal renal function and urinary output
• Caution required in patients with abnormal renal mechanisms
• Potential symptoms of potassium intoxication
• Development of hyperkalemia or alkalosis in certain patients

Pregnancy & Lactation

• No information available regarding use during pregnancy and lactation

Precautions & Warnings

• Use with caution in patients with low urinary output
• Dilute adequately with water to minimize gastrointestinal injury
• Take each dose after meals
• Large doses may cause hyperkalemia and alkalosis

Overdose Effects

• Rarely causes serious hyperkalemia in persons with normal potassium excretory mechanisms
• Hyperkalemia treatment measures
• Elimination of foods or medications containing potassium
• Intravenous administration of dextrose solution containing insulin/dextrose
• Use of exchange resins, hemodialysis, or peritoneal dialysis

Therapeutic Class

• Prevention of repeated kidney stone formation
• Urinary Alkalinizing Agent

Storage Conditions

• Keep below 30°C temperature
• Keep away from light and moisture
• Keep out of the reach of children

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