Intramol 0.5% (Ophthalmic Solution)

5 ml drop: ৳ 70.00

Medicine Details

Category	Details
Generic	Timolol maleate
Company	Beximco pharmaceuticals ltd

Indications

Treatment of elevated intraocular pressure
Ocular hypertension
Open-angle glaucoma

Pharmacology

Non-selective β-adrenergic receptor blocker
Reduction of aqueous humour formation
Lowering of blood pressure

Dosage & Administration

Initial dose of 0.25% solution bid
Potential increase to 0.5% solution bid
Maintenance dose of 0.5% solution once daily
Gel-forming eye drops available in 0.25% and 0.5%
Instill 1 drop into affected eye(s) once daily

Interaction

Possible mydriasis with epinephrine therapy
Noticeable drug interactions with beta-adrenergic blocking agents
Interactions with calcium antagonists, catecholamine-depleting drugs, digitalis, quinidine, clonidine, injectable epinephrine

Contraindications

Bronchial asthma
Severe chronic obstructive pulmonary disease
Sinus bradycardia
Atrioventricular block
Cardiac failure
Cardiogenic shock
Hypersensitivity to any component

Side Effects

Burning and stinging sensation of the eyes
Bradycardia
Hypotension
Arrhythmia
Chronic heart failure
Pulmonary edema
Headache
Dizziness
Asthenia
Abdominal discomfort
Nausea
Constipation
Hypoglycemia

Pregnancy & Lactation

Use during pregnancy only if benefit justifies risk
Detection in breast milk
Serious adverse reactions in nursing infants

Precautions & Warnings

Inadequate cardiac function
Diabetes mellitus
Myasthenia gravis
Cerebrovascular insufficiency
History of atopy
Avoid abrupt withdrawal
Exacerbation of angina symptoms
Precipitation of myocardial infarction
Precipitation of thyroid crisis
Major surgery
Masking signs of hyperthyroidism
Renal and hepatic impairment

Overdose Effects

Dizziness
Headache
Shortness of breath
Bradycardia
Bronchospasm
Cardiac arrest

Therapeutic Class

Drugs for miotics and glaucoma

Storage Conditions

Store between 15-30°C
Avoid freezing
Protect from light

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