Pulmosis 801 mg (Tablet)
Unit Price: ৳ 125.00 (1 x 10: ৳ 1,250.00)
Strip Price: ৳ 1,250.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pirfenidone |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of mild to moderate Idiopathic Pulmonary Fibrosis (IPF) in adults
Pharmacology
- Anti-inflammatory properties
- Antioxidant properties
- Anti-fibrotic properties
- Improvement of lung function
- Reduction of acute exacerbations in IPF patients
- Suppression of TGF-β1
- Downregulation of pro-inflammatory cytokines
Dosage & Administration
- Oral administration with food
- Titration process for initiating treatment
- Recommended daily dose for IPF patients
- Dose adjustments for gastrointestinal events
- Dose adjustments for photosensitivity reaction or rash
- Dose adjustments for hepatic function
Interaction
- Interaction with moderate and strong inhibitors of CYP1A2
- Recommendations for co-administration with food
- Comparison of adverse reaction incidence in fed group vs. fasted group
Contraindications
- Hypersensitivity to active substance or excipients
- Concomitant use of fluvoxamine
- Severe hepatic impairment or end stage liver disease
- Severe renal impairment or end stage renal disease
Side Effects
- Common side effects
- Rare side effects
Pregnancy & Lactation
- Limited data on use in pregnant women
- Precautionary measures for avoiding use during pregnancy
- Unknown excretion in human milk
- Potential risk to the suckling child
- Effects on fertility and reproductive performance in rats
Precautions & Warnings
- Monitoring of liver enzymes
- Precautions for photosensitivity and rash
- Precautions for gastrointestinal disorders
Use in Special Populations
- Safety and effectiveness in children & adolescents
- Hepatic impairment monitoring and recommendations
- Renal impairment monitoring and recommendations
- Effect of smoking on exposure
Overdose Effects
- Limited clinical experience with overdose
- Administration of multiple doses to healthy adult volunteers
- Mild, transient adverse reactions
Therapeutic Class
- Immunosuppressant
Storage Conditions
- Recommendations for storage in a cool & dry place
- Protection from light & moisture
- Keep out of reach of children