Dilitus 200 mcg (Tablet)

Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Voglibose
Company General pharmaceuticals ltd
Also available as
Dilitus 300 mcg tablet

Title

Dilitus

Categories

  • Diabetes Mellitus
  • Anti-diabetic Medication
  • Alpha-Glucosidase Inhibitor

Description

  • Selective inhibitor of α-glucosidase
  • Suppresses sharp increase in post-prandial plasma glucose

Indications

  • Reduction in Post-Prandial Hyperglycaemia (PPHG)
  • Immunotherapy for non-insulin-dependent diabetes mellitus (NIDDM) patients
  • Combination therapy with other Oral Hypoglycaemic Agents (OHAs)
  • Prevention of type 2 diabetes mellitus in impaired glucose tolerance
  • Use in elderly patients and those with hepatic dysfunction or mild to moderate renal impairments
  • Helpful in preventing hypoglycaemia in patients with type lb glycogen storage disease
  • Useful in non-diabetic Hyperinsulinemia
  • Helpful in steroid induced diabetes mellitus

Pharmacology

Inhibits alpha-glucosidase enzymes in the small intestines, delaying carbohydrate digestion and absorption

DosageAndAdministration

  • NormalAdultDose: 0.2 mg, 3 times a day, before each meal
  • Pediatrics: Safety and effectiveness not established
  • Geriatrics: Lower starting dose recommended for elderly patients

Interaction

  • CautionWith:
    • Derivative(s) of sulfonylamide and sulfonylurea
    • Biguanide derivatives
    • Insulin preparations
    • Drugs enhancing or diminishing the hypoglycaemic action of antidiabetic drugs

Contraindications

  • Hypersensitivity to Voglibose or to any excipients
  • Diabetic ketoacidosis, diabetic pre-coma
  • Severe infection, before and after operation or with serious trauma
  • Gastrointestinal obstruction or predisposition to it

SideEffects

  • Diarrhoea
  • Abdominal pain
  • Constipation
  • Nausea
  • Vomiting
  • Increased gas
  • OHAs plus Dilitus may cause hypoglycaemia
  • Serious liver dysfunction with increased liver enzymes
  • Numbness
  • Edema
  • Blurred vision
  • Malaise
  • Weakness
  • Hyperkalemia

PregnancyAndLactation

  • PregnancySafety: Not established
  • LactationSafety: May not be administered to nursing mothers

PrecautionsAndWarnings

  • Caution with other antidiabetic drugs
  • Caution with chronic intestinal disease
  • Caution with serious hepatic or renal dysfunction
  • Caution with elderly patients

UseInSpecialPopulations

  • RenalFailureDosage: No dose adjustment required

OverdoseEffects

  • HypoglycaemiaRisk: Unlike sulfonylureas or insulin, an overdose does not result in hypoglycaemia
  • PossibleEffects:
    • Transient increase in flatulence
    • Diarrhoea
    • Abdominal discomfort
    • No serious systemic reactions expected

TherapeuticClass

Alpha-Glucosidase Inhibitor

StorageConditions

Cool, dry place; protect from light

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