Caloprid 2 mg (Tablet)
Unit Price: ৳ 24.00 (2 x 10: ৳ 480.00)
Strip Price: ৳ 240.00
Medicine Details
Category | Details |
---|---|
Generic | Prucalopride succinate |
Company | Square pharmaceuticals plc |
Also available as |
Indications
- Symptomatic treatment of chronic constipation in adults in whom laxatives fail to provide adequate relief.
Pharmacology
- Selective stimulator of the 5-HT4 receptors
- Acts on smooth muscle cells, enterochromaffin cells, and myenteric plexus
Dosage & Administration
- Adults: 2 mg once daily with or without food
- Older people: Start with 1 mg once daily
Interaction
- Low interaction potential with CYP-mediated metabolism
- Weak substrate for P-glycoprotein
Contraindications
- Hypersensitivity to the active substance or to any of the excipients
- Renal impairment requiring dialysis
Side Effects
- Headache
- Gastrointestinal symptoms (abdominal pain, nausea, diarrhea)
Pregnancy & Lactation
- Not recommended during pregnancy
- Effective contraception advised during treatment
Precautions & Warnings
- Dose adjustment in severe renal impairment
- Caution in severe hepatic impairment
- Possible reduction in efficacy of oral contraceptives with severe diarrhea
- Contains lactose
Use in Special Populations
- Dose adjustment for severe renal impairment and severe hepatic impairment
Overdose Effects
- Symptoms include headache, nausea, and diarrhea
- Supportive treatment for overdose
- Correction of electrolyte disturbances
Therapeutic Class
- Osmotic purgatives
Storage Conditions
- Store at room temperature below 30°C
- Dispense in original bottle