Maclixine 25 mg+50 mg (Tablet)
Unit Price: ৳ 3.01 (5 x 10: ৳ 150.54)
Strip Price: ৳ 30.11
Medicine Details
| Category | Details |
|---|---|
| Generic | Meclizine pyridoxine |
| Company | General pharmaceuticals ltd |
Indications
- Prevention and treatment of nausea
- Prevention and treatment of vomiting
- Prevention and treatment of dizziness
- Prevention and treatment of motion sickness
- Prevention and treatment of radiation sickness
- Prevention and treatment of vertigo
Pharmacology
- Anti-emetic properties
- Anticholinergic properties
- Antihistaminic properties
- Reduction of sensitivity of the labyrinthine apparatus
- Action mediated through nerve pathways to the vomiting center (VC)
- Action mediated through nerve pathways to the chemoreceptor trigger zone (CTZ)
- Peripheral nerve pathways action
- Central nervous system (CNS) centers action
- Addition of vitamin B-6 (pyridoxine) to enhance anti-emetic effects
Dosage & Administration
- Dosage for adults and children aged 12 and over
- Initial doses for various conditions such as nausea, vomiting, motion sickness, radiation sickness, vertigo, and prevention of nausea and vomiting associated with emergency contraceptive pill (ECP)
- Safety and efficacy not established for use in children under 12 years old
Interaction
- Potentiation of CNS depressant effects by Ethanol
- Potentiation of CNS depressant effects by other CNS depressant agents
- Potentiation of anticholinergic effects by other anticholinergics
- Increase in the absorption of digoxin by decreasing gastrointestinal motility
Contraindications
- Hypersensitivity to Meclizine Hydrochloride
- Hypersensitivity to Pyridoxine Hydrochloride
Side Effects
- Reported side effects: drowsiness, dry mouth, blurred vision
Pregnancy & Lactation
- Pregnancy Category B
- Suggested lowest risk of teratogenicity
- Drug of first choice for treating nausea and vomiting during pregnancy
- Safety not established for use in nursing mothers
Precautions & Warnings
- Impairment of ability to perform hazardous activities
- Avoidance of alcoholic beverages
- Use with caution in patients with asthma
- Use with caution in patients with glaucoma
- Use with caution in patients with enlargement of the prostate gland
Overdose Effects
- Symptoms: extreme excitability, seizures, drowsiness, hallucinations
- Treatment: appropriate supportive and symptomatic treatment, consider dialysis
Therapeutic Class
- Anti-emetic drugs
Storage Conditions
- Storage below 30°C temperature
- Storage away from light and moisture
- Storage out of the reach of children