Clacido (1 gm+200 mg)/20 ml (IV Injection)

1.2 gm vial: ৳ 300.00

Medicine Details

Category Details
Generic Amoxicillin clavulanic acid
Company Healthcare pharmaceuticals ltd
Also available as
Clacido 500 mg injection Clacido 875 mg tablet Clacido 250 mg tablet Clacido 500 mg tablet Clacido bid 400 mg suspension Clacido 125 mg suspension

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Genito-urinary tract infections
  • Skin and soft tissue infections
  • Bone and joint infections
  • Bacterial infections
  • Septic abortion
  • Puerperal sepsis
  • Intra-abdominal sepsis

Composition

  • 375 mg tablet
  • 625 mg tablet
  • 1 gm tablet
  • Powder for Suspension
  • Powder for Suspension (Forte)
  • 1.2 gm Injection
  • 0.6 gm injection

Pharmacology

  • Broad spectrum of bactericidal activity
  • Deactivated by beta-lactamases
  • Inactivation of beta-lactamase enzymes
  • Extended antibiotic spectrum

Dosage

  • Usual adult dose of 625 mg tablet every 12 hours
  • Usual adult dose of 375 mg tablet every 8 hours
  • Usual adult dose of 1 gm tablet every 12 hours
  • Suspension dosage for different age groups
  • IV Injection dosage for adults and children

Administration

  • Oral dosage form
  • Enhanced absorption with meal
  • IV administration instructions

Interaction

  • Prolongation of bleeding time
  • Reduction of oral contraceptives efficacy

Contraindications

  • Penicillin hypersensitivity
  • Cross-sensitivity with other beta-lactam antibiotics

Side Effects

  • Gastrointestinal side effects
  • Hepatitis
  • Cholestatic jaundice
  • Skin reactions
  • Angioedema
  • Anaphylaxis

Pregnancy & Lactation

  • No teratogenic effect in animal studies
  • Limited use in human pregnancy
  • Trace quantities in breast milk

Precautions & Warnings

  • Use with care in patients on anticoagulation therapy
  • Dosage adjustment for renal impairment
  • Maintain fluid intake and urinary output

Use in Special Populations

  • Dose adjustment for renal impairment in adults and children

Overdose Effects

  • Unlikely occurrence
  • Gastrointestinal symptoms
  • Fluid and electrolyte balance disturbance
  • Potential removal by haemodialysis

Therapeutic Class

Broad spectrum penicillins

Reconstitution

IV injection reconstitution instructions

Storage Conditions

  • Storage temperature
  • Protection from light and moisture
  • Refrigeration of reconstituted suspension
  • Time constraints for reconstituted vial

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