Clacido 500 mg+125 mg (Tablet)

Unit Price: ৳ 32.00 (3 x 6: ৳ 576.00)
Strip Price: ৳ 192.00

Medicine Details

Category Details
Generic Amoxicillin clavulanic acid
Company Healthcare pharmaceuticals ltd
Also available as
Clacido 500 mg injection Clacido 1 gm injection Clacido 875 mg tablet Clacido 250 mg tablet Clacido bid 400 mg suspension Clacido 125 mg suspension

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Genito-urinary tract infections
  • Skin and soft tissue infections
  • Bone and joint infections
  • Septic abortion
  • Puerperal sepsis
  • Intra-abdominal sepsis

Composition

  • 375 mg tablet
  • 625 mg tablet
  • 1 gm tablet
  • Powder for Suspension
  • Powder for Suspension (Forte)
  • 1.2 gm Injection
  • 0.6 gm injection

Pharmacology

  • Broad spectrum of bactericidal activity
  • Amoxicillin and Clavulanic Acid combination
  • Bactericidal activity against Gram-positive microorganisms
  • Bactericidal activity against Gram-negative microorganisms
  • Inactivation of beta-lactamase enzymes
  • Extended antibiotic spectrum

Dosage

  • Tablet dosage for adults
  • Tablet dosage for children over 12 years
  • Suspension dosage for children
  • Forte suspension dosage
  • IV Injection dosage for adults
  • IV Injection dosage for children

Administration

  • Oral dosage form administration
  • IV injection administration
  • Optimized absorption with meal
  • Intravenous injection guidelines

Interaction

  • Prolongation of bleeding time
  • Reduction of oral contraceptives efficacy
  • Concomitant use of allopurinol
  • Allopurinol and amoxicillin interaction

Contraindications

  • Penicillin hypersensitivity history
  • Cross-sensitivity with other beta-lactam antibiotics
  • Cholestatic jaundice history

Side Effects

  • Mild and transitory side effects
  • Diarrhea
  • Pseudomembranous colitis
  • Indigestion
  • Nausea
  • Vomiting
  • Candidiasis
  • Hepatitis
  • Cholestatic jaundice
  • Urticarial and erythematous rashes
  • Erythema multiforme
  • Stevens-Johnson Syndrome
  • Exfoliative dermatitis
  • Angioedema
  • Anaphylaxis

Pregnancy & Lactation

  • No teratogenic effect
  • Limited human pregnancy use
  • Avoid use in pregnancy unless essential
  • Trace quantities in breast milk

Precautions & Warnings

  • Care in patients on anticoagulation therapy
  • Care in patients with severe hepatic dysfunction
  • Dosage adjustment for renal impairment
  • Adequate fluid intake and urinary output maintenance

Use in Special Populations

  • Dosage adjustment in renal impairment
  • Monitoring hepatic function
  • Dosage caution in hepatic impairment

Overdose Effects

  • Gastrointestinal symptoms
  • Fluid and electrolyte balance disturbance
  • Potential haemodialysis removal

Therapeutic Class

  • Broad spectrum penicillins

Reconstitution

  • IV injection reconstitution process
  • Disallowed reconstitution or mixing

Storage Conditions

  • Storage temperature below 25°C
  • Protection from light and moisture
  • Refrigeration of reconstituted suspension
  • Reconstituted vial usage timeframe

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