Danilo 120 mg (Tablet)

Unit Price: ৳ 14.00 (3 x 10: ৳ 420.00)
Strip Price: ৳ 140.00

Medicine Details

Indications

  • Symptomatic relief of Osteoarthritis (OA)
  • Rheumatoid arthritis (RA)
  • Ankylosing spondylitis
  • Pain and signs of inflammation associated with acute gouty arthritis
  • Short-term treatment of moderate pain associated with dental surgery

Pharmacology

  • Potent, orally active COX-2 specific inhibitor
  • Inhibition of COX-2 decreases clinical signs and symptoms
  • Selective inhibition of COX-2 decreases potential for GI toxicity
  • Did not inhibit gastric prostaglandin synthesis

Dosage & Administration

  • Recommended doses for different conditions: 30mg, 60mg, 90mg, 120mg once daily
  • Shortest duration and lowest effective daily dose is recommended

Interaction

  • With medicine: Oral anticoagulants, Diuretics, ACE inhibitors, Acetylsalicylic Acid, Ciclosporin and tacrolimus, Lithium
  • With food & others: Take without regards to meals

Contraindications

  • Hypersensitivity to active substance or excipients
  • Active peptic ulceration or active GI bleeding
  • Patients with specific allergic-type reactions
  • Pregnancy, lactation, severe hepatic dysfunction, estimated renal creatinine clearance <30 ml/min, children and adolescents under 16 years of age, inflammatory bowel disease, congestive heart failure, hypertension, established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease

Side Effects

  • Palpitation, fatigue, influenza-like symptoms
  • Dry mouth, taste disturbance, mouth ulcer, appetite and weight change
  • Atrial fibrillation, transient ischaemic attack, chest pain
  • Flushing, cough, dyspnoea, epistaxis, anxiety
  • Myalgia, arthralgia, confusion, hallucinations

Pregnancy & Lactation

  • Not recommended in women attempting to conceive
  • Not known whether excreted in human milk
  • Not recommended for breastfeeding women

Precautions & Warnings

  • Caution in patients at risk of GI complications with NSAIDs
  • Caution in patients with significant risk factors for cardiovascular events
  • Monitoring of renal function should be considered
  • Caution in patients with history of cardiac failure, left ventricular dysfunction, hypertension or pre-existing edema
  • Monitoring of liver function should be considered
  • Caution in co-administration with warfarin or other oral anticoagulants

Overdose Effects

  • Single doses up to 500mg and multiple doses up to 150mg/day did not result in significant toxicity
  • Usual supportive measures recommended in case of overdose

Therapeutic Class

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Store at temperature below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C18H15ClN2O2S
  • Chemical Structure: Image available

Common Questions about Danilo 120 mg Tablet

  • What is Danilo 120 mg Tablet?
  • What are the uses of Danilo 120 mg Tablet?
  • Duration of effect of Danilo 120 mg Tablet
  • Onset of action of Danilo 120 mg Tablet
  • Pregnancy warnings of Danilo 120 mg Tablet
  • Habit forming tendencies
  • Breast-feeding warnings
  • Safety with alcohol
  • Safety to drive while on this medicine
  • Effect on kidney function
  • Effect on liver function
  • Quick Tips

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