Danilo 90 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoricoxib |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Title
- Danilo 90 mg Tablet
Categories
- Pain Relief
- NSAIDs
- Anti-inflammatory Drugs
Description
- Symptomatic relief of Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, acute gouty arthritis, postoperative dental surgery pain
Dimensions
- Tablet form
Color options
Functions
- COX-2 specific inhibitor
- Inhibition of prostaglandin-mediated pain, inflammation, and fever
Materials
Technical specifications
- Molecular Formula: C18H15ClN2O2S
Design elements
Usability features
- Orally active
- Fast onset of action (1-2 hours)
- Duration of effect: 20-24 hours
Indications
- Osteoarthritis
- Rheumatoid arthritis
- Ankylosing spondylitis
- Acute gouty arthritis
- Pain after dental surgery
- Moderate pain relief
Pharmacology
- Selective COX-2 inhibition
- COX-2 mediated pain relief
- Decreased potential for GI toxicity
- Decreased platelet aggregation
Dosage administration
- Adult & Adolescent over 16 years:
- Osteoarthritis: 30 mg once daily, may increase to 60 mg for insufficient relief
- Rheumatoid arthritis: 90 mg once daily
- Ankylosing spondylitis: 90 mg once daily
- Acute gouty arthritis: 120 mg once daily for 8 days
- Postoperative dental surgery pain: 90 mg once daily, max 3 days
- Additional: Shortest duration and lowest effective dose recommended due to cardiovascular risks
Interaction
- Oral anticoagulants may increase prothrombin time
- NSAIDs may reduce the effect of diuretics and antihypertensive drugs
- May be used concomitantly with low-dose acetylsalicylic acid for cardiovascular prophylaxis
Contraindications
- Hypersensitivity to active substance or excipients
- Active peptic ulceration or Gl bleeding
- History of hypersensitivity reactions to NSAIDs or COX-2 inhibitors
- Pregnancy and lactation
- Severe hepatic dysfunction
- Estimated renal creatinine clearance <30 ml/min
- Children & adolescents under 16 years
- Inflammatory bowel disease
- Congestive heart failure
- Uncontrolled hypertension
- Established ischaemic heart disease
Side effects
- Palpitation
- Fatigue
- Influenza-like symptoms
- Dry mouth
- Taste disturbance
- Mouth ulcer
- Atrial fibrillation
- Chest pain
- Flushing
- Cough
- Dyspnoea
- Anxiety
- Paraesthesia
- Myalgia
- Arthralgia
- Confusion
- Hallucinations
Pregnancy lactation
- Not recommended for women attempting to conceive
- Not to be used during breastfeeding
Precautions warnings
- Caution in patients at risk of GI complications with NSAIDs
- Use with caution in patients with cardiovascular risk factors
- Monitoring of renal function advised
- Caution in patients with cardiac failure, hypertension, or edema
- Monitoring of liver function recommended
- Discontinue at first sign of hypersensitivity or skin rash
- May mask fever and signs of inflammation
- Caution with concurrent use of warfarin or other oral anticoagulants
Overdose effects
- Single doses up to 500 mg and multiple doses up to 150 mg/day did not result in significant toxicity
- Usual supportive measures to be employed in case of overdose
Therapeutic class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage conditions
- Store below 30°C, protect from light & moisture, keep out of reach of children
Common questions
- Duration of effect
- Onset of action
- Pregnancy warnings
- Habit forming
- Breastfeeding warnings
- Safe with alcohol
- Safe to drive while on this medicine
- Effect on kidney function
- Effect on liver function