Zolivox 400 mg (Tablet)

Unit Price: ৳ 60.00 (1 x 10: ৳ 600.00)
Strip Price: ৳ 600.00

Medicine Details

Category Details
Generic Linezolid
Company Square pharmaceuticals plc
Also available as
Zolivox 600 mg tablet

Product Title

  • Zolivox

Categories

  • Medicine
  • Antibiotic
  • Pharmacology
  • Therapeutic Class: Macrolides

Indications

  • Treatment of nosocomial pneumonia
  • Treatment of community-acquired pneumonia
  • Treatment of complicated skin and skin structure infection including diabetic foot infections
  • Treatment of uncomplicated skin and skin structure infections
  • Treatment of vancomycin-resistant Enterococcus faecium infections

Mode of Action

  • Selectively inhibits bacterial protein synthesis
  • Binds to the 23S ribosomal RNA of the 50S subunit
  • Prevents the formation of a functional 70S initiation complex

Dosage & Administration

  • Oral administration with or without food
  • Intravenous administration over 30 to 120 minutes
  • Dosage varies based on infection type and patient age
  • No dose adjustment necessary when switching from IV to oral administration
  • Special considerations for use in pediatric patients and neonates

Interaction

  • Potential for interaction with adrenergic and serotonergic agents
  • Advising patients to avoid large quantities of foods or beverages with high tyramine content

Contraindications

  • Hypersensitivity to Linezolid or any of the other product components
  • Use with monoamine oxidases A or B inhibitors
  • Uncontrolled hypertension, pheochromocytoma, thyrotoxicosis
  • Use with sympathomimetic, vasopressive, or dopaminergic agents

Side Effects

  • Mild to moderate adverse events
  • Common adverse events: diarrhea, headache, nausea
  • Other adverse events include hypertension, dyspepsia, and localized abdominal pain

Pregnancy & Lactation

  • Linezolid should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus
  • Consideration of breastfeeding benefits and potential adverse effects on the breastfed child

Precautions & Warnings

  • Monitoring complete blood counts in patients receiving Zolivox
  • Prompt ophthalmic evaluation if visual impairment symptoms occur
  • Not approved for the treatment of catheter-related bloodstream infections or catheter-site infections

Overdose Effects

  • No cases of overdose reported
  • Symptomatic and supportive care advised

Reconstitution

  • Oral Suspension: Instructions for reconstitution and storage
  • Intravenous Administration: Guidelines for administration and storage

Storage Conditions

  • Store at room temperature (15°C-30°C)
  • Store away from light and moisture
  • Keep away from children

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