Eparin 4000 Anti-Xa IU/0.4 ml (SC Injection)

0.4 ml pre-filled syringe: ৳ 450.00

Medicine Details

Category Details
Generic Enoxaparin sodium
Company Beacon pharmaceuticals plc
Also available as
Eparin 6000 anti xa injection

Title

  • Eparin

Category

  • Medicine
  • Health & Wellness

Description

  • Eparin is indicated in the treatment of deep vein thrombosis, unstable angina, non-Q-wave myocardial infarction, prevention of thrombus formation in the extra-corporeal circulation during haemodialysis, and prophylaxis of venous thromboembolic disease in various medical and surgical conditions.

Color Options

  • NA

Function

  • Anticoagulant
  • Prevent thrombus formation
  • Treat deep vein thrombosis
  • Treat myocardial infarction
  • Prevent thrombus during hemodialysis
  • Prophylaxis of venous thromboembolic disease

Material

  • Enoxaparin Sodium BP

Technical Specifications

  • Each 0.2 ml pre-filled syringe contains Enoxaparin Sodium BP 20 mg equivalent to 2000 anti-Xa III
  • Each 0.4 ml pre-filled syringe contains Enoxaparin Sodium BP 40 mg equivalent to 4000 anti-Xa III
  • Each 0.6 ml pre-filled syringe contains Enoxaparin Sodium BP 60 mg equivalent to 6000 anti-Xa IU
  • Each 0.8 ml pre-filled syringe contains Enoxaparin Sodium BP 80 mg equivalent to 8000 anti-Xa IU
  • Low molecular weight heparin
  • High anti-Xa activity
  • Low anti-IIa or antithrombin activity
  • Primary metabolism in the liver
  • Parenteral anti-coagulants

Design Elements

  • Pre-filled syringe

Usability Features

  • Subcutaneous injection
  • Intravascular administration during hemodialysis
  • Deep subcutaneous route in prophylactic and curative treatment

Dimensions

  • NA

Indications

  • Treatment of deep vein thrombosis
  • Treatment of unstable angina and non-Q-wave myocardial infarction
  • Prevention of thrombus formation in the extra-corporal circulation during haemodialysis
  • Prophylaxis of venous thromboembolic disease

Composition

  • Enoxaparin Sodium BP 20 mg
  • Enoxaparin Sodium BP 40 mg
  • Enoxaparin Sodium BP 60 mg
  • Enoxaparin Sodium BP 80 mg

Pharmacology

  • High anti-Xa activity
  • Low anti-IIa or antithrombin activity
  • No notable modification of activated Partial Thromboplastin Time (aPTT)
  • No influence on platelet aggregation or binding of fibrinogen to platelets

Dosage

  • Different dosages for different indications
  • Subcutaneous and oral administration

Administration

  • Subcutaneous and intravascular administration
  • Instructions for self-injection
  • Dose selection and injection techniques
  • Disposal after use

Interaction

  • Discontinuation of agents affecting hemostasis prior to Eparin therapy
  • Recommendations for careful clinical and laboratory monitoring

Contraindications

  • Known hypersensitivity to Enoxaparin Sodium
  • Active major bleeding
  • High risk of uncontrolled hemorrhage

Side Effects

  • Haemorrhage
  • Thrombocytopenia
  • Elevations of serum aminotransferase
  • Pain and skin rash at injection sites
  • Neuraxial hematomas with concurrent use of Eparin and spinal/epidural anesthesia

Pregnancy & Lactation

  • Pregnancy category B
  • Risk for pregnant women with mechanical prosthetic heart valves
  • Unknown excretion in human milk

Precautions & Warnings

  • Deep subcutaneous and intravascular administration
  • Caution in conditions with increased potential for bleeding
  • Platelet count monitoring

Use in Special Populations

  • Dose in Elderly Patients
  • Dose in Renal Impairment
  • Dose in Hepatic Impairment

Overdose Effects

  • Hemorrhagic complications
  • Neutralization with protamine sulfate

Therapeutic Class

  • Parenteral anti-coagulants

Storage Conditions

  • Cool and dry place
  • Protection from light and moisture
  • Temperature limitation
  • Keep out of the reach of children

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