Xelmet 850 mg (Tablet)

Unit Price: ৳ 6.50 (6 x 10: ৳ 390.00)
Strip Price: ৳ 65.00

Medicine Details

Indications

  • Treatment of type 2 diabetes mellitus
  • Monotherapy for adults
  • Combination therapy for children and adolescents
  • Reduction of diabetic complications

Pharmacology

  • Biguanide type oral antihyperglycemic drug
  • Lowers basal and postprandial plasma glucose
  • Improves insulin sensitivity
  • Decreases hepatic glucose production

Dosage & Administration

  • Individualized dosage based on effectiveness and tolerance
  • Usual starting dose for adults and children
  • Extended release tablet instructions
  • Renal impaired patient precautions

Interaction

  • No chronic co-administration information available
  • Enhanced absorption with Nifedipine
  • Potential for interaction with cationic drugs
  • Certain drugs leading to hyperglycemia

Contraindications

  • Hypersensitivity to active substance or excipients
  • Acute metabolic acidosis
  • Severe renal failure
  • Conditions altering renal function

Side Effects

  • Hemolytic anemia
  • Lactic acidosis
  • Decrease of vitamin B12 absorption
  • Peripheral neuropathy
  • Gastrointestinal disorders
  • Liver function test abnormalities
  • Skin reactions

Pregnancy & Lactation

  • Increased risk of congenital abnormalities
  • Insulin recommended for diabetes during pregnancy
  • Excretion into breast milk

Precautions & Warnings

  • Risk of lactic acidosis with impaired renal function
  • Lowered vitamin B12 level
  • Increased risk of hypoglycemia with insulin combination
  • Special precautions for elderly and pediatric population

Use in Special Populations

  • Dosage adjustment for elderly with decreased renal function
  • No effect on growth and puberty detected
  • Renal function assessment before and during treatment

Overdose Effects

  • Hypoglycemia not seen at certain doses
  • Lactic acidosis as medical emergency
  • Hemodialysis for lactate and drug removal

Therapeutic Class

  • Biguanides

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

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