Xelmet 850 mg (Tablet)
Unit Price: ৳ 6.50 (6 x 10: ৳ 390.00)
Strip Price: ৳ 65.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Beacon pharmaceuticals plc |
| Also available as |
Indications
- Treatment of type 2 diabetes mellitus
- Monotherapy for adults
- Combination therapy for children and adolescents
- Reduction of diabetic complications
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers basal and postprandial plasma glucose
- Improves insulin sensitivity
- Decreases hepatic glucose production
Dosage & Administration
- Individualized dosage based on effectiveness and tolerance
- Usual starting dose for adults and children
- Extended release tablet instructions
- Renal impaired patient precautions
Interaction
- No chronic co-administration information available
- Enhanced absorption with Nifedipine
- Potential for interaction with cationic drugs
- Certain drugs leading to hyperglycemia
Contraindications
- Hypersensitivity to active substance or excipients
- Acute metabolic acidosis
- Severe renal failure
- Conditions altering renal function
Side Effects
- Hemolytic anemia
- Lactic acidosis
- Decrease of vitamin B12 absorption
- Peripheral neuropathy
- Gastrointestinal disorders
- Liver function test abnormalities
- Skin reactions
Pregnancy & Lactation
- Increased risk of congenital abnormalities
- Insulin recommended for diabetes during pregnancy
- Excretion into breast milk
Precautions & Warnings
- Risk of lactic acidosis with impaired renal function
- Lowered vitamin B12 level
- Increased risk of hypoglycemia with insulin combination
- Special precautions for elderly and pediatric population
Use in Special Populations
- Dosage adjustment for elderly with decreased renal function
- No effect on growth and puberty detected
- Renal function assessment before and during treatment
Overdose Effects
- Hypoglycemia not seen at certain doses
- Lactic acidosis as medical emergency
- Hemodialysis for lactate and drug removal
Therapeutic Class
- Biguanides
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children