Pendoril Plus 2 mg+0.625 mg (Tablet)
Unit Price: ৳ 10.00 (2 x 10: ৳ 200.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Perindopril indapamide |
| Company | Renata limited |
| Also available as |
Indications
- Treatment of essential hypertension
- Blood pressure management
Pharmacology
- Nonsulphydryl ACE inhibitor
- Treatment of hypertension
- Conversion of angiotensin I to angiotensin II
- Stimulation of aldosterone secretion
- Inhibition of ACE activity
- Decreased vasoconstriction
- Increased plasma renin activity
- Interference with the degradation of bradykinin
Dosage & Administration
- 1-2 tablets per day
- Morning administration
- Preferably taken before a meal
- Adjusted dosage for renal insufficiency
Interaction
- Potentiation of hypotensive effects
- Reduction of antihypertensive effect by NSAIDs
- Risk of hyperkalemia with ARB and Potassium Sparing diuretics
Contraindications
- Hypersensitivity to perindopril/ indapamide
- Hypersensitivity to any other ACE inhibitor
Side Effects
- Nausea
- Vomiting
- Dyspepsia
- Diarrhea
- Constipation
- Headache
- Dizziness
- Sleep disturbance
- Asthenia
- Dry mouth
- Hypotension
- Persistent dry cough
- Angioedema
- Rash
Pregnancy & Lactation
- Not recommended in pregnancy
- Not recommended for breastfeeding mothers
Precautions & Warnings
- Cautious use in renal impairment
- Cautious use in renal artery stenosis
- Cautious use in heart failure
- Cautious use in gout
- Cautious use in diabetes
- Cautious use in liver cirrhosis
- Cautious use in elderly patients
- Cautious use in atherosclerosis
- Cautious use in idiopathic or hereditary angioedema
Overdose Effects
- Hypotension
- Nausea
- Vomiting
- Cramps
- Dizziness
- Sleepiness
- Mental confusion
- Oliguria
- Anuria
- Salt and water disturbances
- Gastric lavage
- Activated charcoal administration
- Fluid and electrolyte balance monitoring
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Store below 30°C