Velatas 400 mg+100 mg (Tablet)
Unit Price: ৳ 1,000.00 (1 x 7: ৳ 7,000.00)
Strip Price: ৳ 7,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sofosbuvir velpatasvir |
| Company | Healthcare pharmaceuticals ltd |
Indications
- Hepatitis C virus (HCV) treatment
- Chronic HCV genotype 1-6 infection
- With or without cirrhosis
- Pediatric patients 3 years and older
Pharmacology
- Inhibitor of HCV NS5B RNA-dependent RNA polymerase
- Inhibitor of HCV NS5A protein
- Chain terminator for viral replication
- Effect on QTc interval evaluation
Dosage & Administration
- Recommended regimen for adults and pediatric patients
- Dosage for adults and pediatric patients
- Testing prior to initiation of therapy
Interaction
- Substrates of drug transporters P-gp and BCRP
- Metabolic turnover by CYP2B6, CYP2C8, and CYP3A4
- Effects on plasma concentrations of other drugs
Contraindications
- Contraindicated in certain patients for whom Ribavirin is contraindicated
Side Effects
- Common side effects
- Rare adverse events
- Serious symptomatic bradycardia with coadministration
Pregnancy & Lactation
- Contraindicated in pregnant women and men with pregnant partners if administered with Ribavirin
Precautions & Warnings
- Risk of Hepatitis B Virus Reactivation
- Serious symptomatic bradycardia with amiodarone coadministration
- Risks associated with Ribavirin and Sofosbuvir & Velpatasvir combination treatment
Use in Special Populations
- Effects on geriatric patients
- Pharmacokinetics in patients with renal impairment
- Pharmacokinetics in patients with hepatic impairment
Overdose Effects
- No specific antidote available
- General supportive measures for treatment
- Hemodialysis efficiency for metabolite removal
Therapeutic Class
- Hepatic viral infections (Hepatitis C)
Storage Conditions
- Store in cool and dry place below 30°C
- Keep out of reach of children