Thoraz 250 mg (Tablet)
Unit Price: ৳ 25.00 (2 x 6: ৳ 300.00)
Strip Price: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Azithromycin dihydrate |
| Company | Al madina pharmaceuticals ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Upper respiratory tract infections
- Otitis media
- Skin and soft tissue infections
- Non-gonococcal urethritis
- Cervicitis due to Chlamydia trachomatis
Pharmacology
- Time to peak concentration: 2.1 to 3.2 hours
- Active transportation to site of infection
- High concentration in phagocytes
- Binding to 50S ribosomal subunit
- Interference with microbial protein synthesis
Dosage
- Adult dosage: 500 mg once daily orally for 3 days
- Children dosage: 10 mg/kg body weight once daily for 3 days
- IV infusion dosage for adult patients with pneumonia
Administration
- Oral administration
- Reconstitution procedure for suspension
- Should be taken at least 1 hour before or 2 hours after meal
Interaction
- Interaction with antacids
- Potential interaction with carbamazepine
- Interference with cyclosporin metabolism
- Impairment of digoxin metabolism
- Potential risk of ergotism
- No significant pharmacokinetic interaction with theophylline
Contraindications
- Hypersensitivity to Azithromycin or macrolide antibiotics
- Co-administration with ergot derivatives
- Patients with hepatic diseases
Side Effects
- Gastrointestinal side-effects
- Allergic reactions such as rash or photosensitivity
- Reversible elevations in liver transaminases
- Rare cases of cholestatic jaundice
- Transient mild reductions in neutrophil counts
- Reversible hearing impairment
Pregnancy & Lactation
- Pregnancy Category B
- No adequate and well controlled studies in pregnant women
- Caution required during nursing
Precautions & Warnings
- Rare serious allergic reactions reported
- Recurrent symptoms of allergic reactions
- Caution in patients with renal impairment
- Avoid use in patients with hepatic impairment
Overdose Effects
- Typical symptoms of macrolide antibiotics overdose
- Indication of gastric lavage and supportive measures
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C38H72N2O12
- Chemical Structure Image
Common Questions about Thoraz 250 mg Tablet
- Action of Thoraz 250 mg Tablet
- Uses of Thoraz 250 mg Tablet
- Side Effects of Thoraz 250 mg Tablet
- Storage and disposal instructions
- Possibility of diarrhea
- Safety of Thoraz 250 mg Tablet
- Classification as an antibiotic
- Course of action if symptoms persist