Hypen Plus 4 mg+1.25 mg (Tablet)
Unit Price: ৳ 12.09 (2 x 14: ৳ 338.52)
Strip Price: ৳ 169.26
Medicine Details
| Category | Details |
|---|---|
| Generic | Perindopril indapamide |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Treatment of essential hypertension
- Blood pressure control
Pharmacology
- Nonsulphydryl ACE inhibitor
- Hydrolysis to active metabolite
- Inhibition of angiotensin II
- Stimulation of aldosterone secretion
- Decreased vasoconstriction
- Increased serum potassium
- Increased plasma renin activity
- Interference with bradykinin degradation
Dosage & Administration
- 1-2 tablets per day
- Morning administration
- Preferably before a meal
- Dose adjustment for renal insufficiency
Interaction
- Potentiation of hypotensive effects
- Reduction of antihypertensive effect
- Potential for hyperkalemia
Contraindications
- Hypersensitivity to perindopril/indapamide
- Hypersensitivity to ACE inhibitors
Side Effects
- Nausea
- Vomiting
- Dyspepsia
- Diarrhea
- Constipation
- Headache
- Dizziness
- Sleep disturbance
- Asthenia
- Dry mouth
- Hypotension
- Persistent dry cough
- Angioedema
- Rash
Pregnancy & Lactation
- Not recommended in pregnancy
- Not recommended during breastfeeding
Precautions & Warnings
- Use cautiously in renal impairment
- Use cautiously in renal artery stenosis
- Use cautiously in heart failure
- Use cautiously in gout
- Use cautiously in diabetes
- Use cautiously in liver cirrhosis
- Use cautiously in elderly patients
- Use cautiously in atherosclerosis
- Use cautiously in idiopathic or hereditary angioedema
Overdose Effects
- Hypotension
- Nausea
- Vomiting
- Cramps
- Dizziness
- Sleepiness
- Mental confusion
- Oliguria
- Anuria
- Salt and water disturbances
- Gastric lavage
- Activated charcoal administration
- Fluid and electrolyte balance monitoring
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Store below 30°C