Claviator-CV (125 mg+31.25 mg)/5 ml (Powder for Suspension)

70 ml bottle: ৳ 250.00

Medicine Details

Category Details
Generic Cefuroxime axetil clavulanic acid
Company Al madina pharmaceuticals ltd
Also available as
Claviator cv 250 mg tablet Claviator cv 500 mg tablet

Title

Claviator-CV 125 Suspension

Categories

  • Pharmaceuticals
  • Antibiotics

Description

Claviator-CV 125 Suspension is a cephalosporin antibiotic used to treat various bacterial infections. It consists of Cefuroxime, a second-generation cephalosporin, and Clavulanic acid, a beta-lactamase inhibitor.

Formulation

Suspension

Dosage strength

125 mg/5ml

Packaging

  • Bottle
  • Box

Age group

  • Adults
  • Adolescents
  • Paediatric Patients

Indication

  • Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
  • Acute Bacterial Otitis Media caused by various bacteria
  • Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
  • Lower respiratory tract infections including pneumoniae caused by various bacteria
  • Uncomplicated skin and skin-structure infections caused by Staphylococcus aureus
  • Uncomplicated urinary tract infections caused by E.coli or Klebsiella pneumoniae
  • Bone and Joint Infections caused by Staphylococcus aureus
  • Uncomplicated Gonorrhoea caused by Neisseria gonorrhoeae
  • Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
  • Septicemia caused by various bacteria
  • Meningitis caused by various bacteria
  • Switch therapy (Injectable to oral)

Pharmacology

Cefuroxime inhibits bacterial cell wall synthesis, while Clavulanic acid protects Cefuroxime from degradation by beta-lactamase enzymes.

Dosage and administration

  • Adolescents and adults:
    • Pharyngitis/tonsillitis: 250 mg b.i.d. for 5-10 days
    • Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
    • Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days
    • Secondary bacterial infections of acute bronchitis: 250-500 mg b.i.d. for 5-10 days
    • Uncomplicated skin and skin structure infections: 250-500 mg b.i.d. for 10 days
    • Uncomplicated urinary tract infections: 250 mg b.i.d. for 7-10 days
    • Uncomplicated Gonorrhoea: 1000 mg b.i.d. Single dose
    • Community acquired pneumonia: 250-500 mg b.i.d. for 5-10 days
    • MDR Typhoid Fever: 500 mg b.i.d. for 10-14 days
    • Early Lyme disease: 500 mg b.i.d. for 20 days
  • Paediatric patients:
    • Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
    • Acute otitis media: 30 mg/kg/day b.i.d for 10 days
    • Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days
    • Impetigo: 30 mg/kg/day b.i.d for 10 days
  • Administration notes: Tablet may be taken without regard for food.

Interaction

Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the serum concentration. Drugs reducing gastric acidity may lower Cefuroxime bioavailability.

Contraindications

  • Known allergy to cephalosporin
  • Pseudomembranous Colitis

Side effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort or pain
  • Renal dysfunction (rare)
  • Anaphylaxis (rare)
  • Angioedema (rare)

Pregnancy and lactation

Safe for use in later pregnancy. Excreted into breast milk in small quantities.

Precautions and warnings

  • Concurrent treatment with potent diuretics
  • History of colitis

Therapeutic class

Second generation Cephalosporins

Storage conditions

Store in a cool, dry place (below 30°C), away from light and moisture. Keep out of the reach of children.

Commonly asked questions

  • What is it: Claviator-CV 125 Suspension is a cephalosporin antibiotic and beta-lactamase inhibitor used for treating various infections.
  • What is it used for: It is used to treat pharyngitis, tonsillitis, sinusitis, bronchitis, SSTI, UTI, gonorrhoea, pneumonia, typhoid fever.
  • How long to take effect: Starts working within 2-3 hours.
  • Duration of effect: Lasts for an average duration of 4-8 hours.
  • Alcohol interaction: Interaction with alcohol is unknown. Consult your doctor before consumption.
  • Habit forming: No habit-forming tendencies reported.
  • Pregnancy usage: Safe to use in pregnancy after consulting a doctor.
  • Breastfeeding usage: Safe to use during breastfeeding at low levels. Exercise caution to avoid sensitizing the infant.
  • Quick tips:
    • Take the full course of treatment even if you feel better.
    • Take with food to avoid an upset stomach.
    • Stop and inform your doctor if you develop an itchy rash, swelling, or breathing difficulties.
    • Do not use leftover medicine for future infections without consulting your doctor.

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