Rynofex 120 mg (Tablet)
Unit Price: ৳ 6.50 (5 x 10: ৳ 325.00)
Strip Price: ৳ 65.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fexofenadine hydrochloride |
| Company | Al madina pharmaceuticals ltd |
| Also available as |
Indications
- Relief of symptoms associated with seasonal and perennial allergic rhinitis
- Relief of symptoms associated with chronic idiopathic urticaria
- Improves health-related quality of life and work/activity productivity
Pharmacology
- H1 histamine receptor mediating hypersensitivity
- Degranulation of mast cells and basophils
- Release of histamine and other inflammatory mediators
- Fexofenadine considered an "inverse agonist" of the H1 receptor
- Selective affinity for H1 receptors
- No evidence of antidopaminergic, antiserotonergic, anticholinergic, sedative, or adrenergic blocking activity
- Does not cross the blood-brain barrier
Dosage & Administration
- Adult dosage: 60 mg twice daily, 120 mg once daily, or 180 mg once daily
- Child dosage: varies based on age and renal function
- Tablet and suspension formulations available
Interaction
- No hepatic biotransformation
- Increased fexofenadine level with erythromycin or ketoconazole
- No interaction with omeprazole
- Reduction in bioavailability with aluminium and magnesium hydroxide
Contraindications
- Known hypersensitivity to Fexofenadine Hydrochloride or its ingredients
Side Effects
- Headache
- Drowsiness
- Dizziness
- Nausea
- Fatigue
- Hypersensitivity reactions
- Insomnia
- Tachycardia
- Palpitations
- Diarrhea
- Rash
- Urticaria
- Pruritus
Pregnancy & Lactation
- Limited data in pregnant women
- No data on human milk content
- Not recommended for breastfeeding mothers
- No human data on effect on fertility
Precautions & Warnings
- Limited data in older people and renally or hepatically impaired patients
- Administer with care in special groups
- Warnings for patients with cardiovascular disease
- Unlikely to produce significant effects on driving or machine use
- Altered pharmacokinetics in elderly patients
Use in Special Populations
- Altered pharmacokinetics in renal impairment
- No substantial effect in moderate to severe hepatic disease
- Similar adverse events in elderly patients
Overdose Effects
- Dizziness
- Drowsiness
- Fatigue
- Dry mouth
- No clinically significant adverse reactions up to 800 mg doses
- Standard measures for removal of unabsorbed product
- Symptomatic and supportive treatment recommended
- Haemodialysis not effective for removal
Therapeutic Class
- Non-sedating antihistamines
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C32H39NO4
- Chemical Structure Image Available
Common Questions about Rynofex 120 mg Tablet
- Antihistamine medication
- Blocks histamine during allergic reaction
- Used for allergic rhinitis and urticaria
- Reported side effects include vomiting, headache, coughing, diarrhea, hives, and more
- Instructions for storage and disposal
- Potential to cause sleepiness
- Onset of action within 1 hour
- Instructions regarding dizziness, antacids, meal consumption, and heart problems
- Quick tips for usage