Ventilast 10 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Montelukast sodium |
| Company | Al madina pharmaceuticals ltd |
Title
Ventilast 10 mg Tablet
Categories
- Medicine
- Healthcare
- Pharmacology
Description
Ventilast is indicated for prophylaxis and chronic treatment of asthma, acute prevention of Exercise-Induced Bronchoconstriction (EIB), and relief of symptoms of Allergic Rhinitis (AR) including seasonal & perennial allergic rhinitis.
DosageInstructions
- Adults and adolescents: Montelukast 10 mg tablet once daily
- Pediatric patients 6 to 14 years: Montelukast 5 mg tablet once daily
- Pediatric patients 2 to 5 years: Montelukast 4 mg tablet once daily
- Pediatric patients 6 months to 5 years: Montelukast 4 mg oral granules once daily
IndicatedFor
- Prophylaxis of Asthma
- Chronic Treatment of Asthma
- Acute Prevention of EIB
- Relief of Allergic Rhinitis Symptoms
PharmacologicalAction
Montelukast is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotriene receptor (CysLT1).
Pathophysiology
Cysteinyl leukotrienes and leukotriene receptor occupation have been correlated with the pathophysiology of asthma and allergic rhinitis, including airway edema, smooth muscle contraction, and altered cellular activity associated with the inflammatory process.
AgeGroupDosage
- Adults and Adolescents: 15 years and older
- Pediatric Patients:
- 6 to 14 years
- 2 to 5 years
- 6 months to 5 years
SafetyAndEfficacy
- HepaticInsufficiency: No dosage adjustment required
- RenalInsufficiency: No dosage adjustment recommended
- ElderlyUse: Similar pharmacokinetic profile to younger adults, slightly longer plasma half-life
InteractionStudies
- NoClinicallyImportantEffectsOn:
- Theophylline
- Prednisone
- Prednisolone
- Oral Contraceptives
- Terfenadine
- Digoxin
- Warfarin
- ConcomitantUseWithNoEvidenceOfClinicalAdverseInteractions:
- Thyroid Hormones
- Sedative Hypnotics
- NSAIDs
- Benzodiazepines
- Decongestants
- PhenobarbitalEffect: Decreased AUC of Montelukast by approximately 40%
Contraindications
Hypersensitivity to any component of this product
SideEffects
- Common:
- Diarrhoea
- Fever
- Gastrointestinal Discomfort
- Headache
- Uncommon:
- Anxiety
- Arthralgia
- Depression
- Dizziness
- Rare:
- Angioedema
- Eosinophilic Granulomatosis
- Hallucination
- Suicidal Tendencies
PregnancyAndLactation
Caution should be exercised when used during pregnancy and lactation
PrecautionsAndWarnings
- Not indicated for reversal of bronchospasm in acute asthma attacks
- Appropriate rescue medication should be available
- Should not be abruptly substituted for inhaled or oral corticosteroids
- Not to be used as monotherapy for exercise induced bronchospasm
OverdoseEffects
- AdverseExperiences:
- Abdominal Pain
- Somnolence
- Thirst
- Headache
- SupportiveMeasures: Remove unabsorbed material, employ clinical monitoring, and institute supportive therapy
TherapeuticClass
Leukotriene Receptor Antagonists
StorageConditions
Store in cool & dry place below 30°C, protect from light & moisture, keep out of reach of children
CompoundSummary
- MolecularFormula: C35H36ClNO3S
- ChemicalStructure: https://medex.com.bd/storage/res/g-res-768-montelukast-sodium-chemical-structure-drK1lRHjspWQ7613gJoZ.svg
CommonQuestions
- What is Ventilast 10 mg Tablet?
- What is Ventilast 10 mg Tablet used for?
- How soon can the effect be observed?
- How long does the effect last?
- Should it be taken empty stomach?
- Are there any pregnancy warnings?
- General Instructions