Xiroket 30 mg/ml (IM/IV Injection)

1 ml ampoule: ৳ 55.00

Medicine Details

Indications

  • Short-term management of post-operative pain
  • Relief of inflammation and light sensitivity after ocular surgery
  • Decrease in eye inflammation or redness caused by seasonal allergies

Description

  • Belongs to pyrrolo-pyrrole group of NSAIDs
  • Inhibits synthesis of prostaglandins
  • Mainly metabolized in the liver

Pharmacology

  • Acts by inhibiting the cyclooxygenase enzyme system
  • Demonstrates minimal anti-inflammatory effect at analgesic dose

Dosage & Administration

  • Recommended tablet dose: 10mg every 4-6 hours
  • IM/IV single-dose treatment based on age and weight
  • Country-specific usage guidelines

Interaction

  • Increased side effects with other NSAIDs or aspirin
  • Enhanced anticoagulant effect with anticoagulants
  • Reduced antihypertensive effect with beta blockers

Contraindications

  • Hypersensitivity to Ketorolac or other NSAIDs
  • Children under 16 years of age
  • Prophylactic use before surgery

Side Effects

  • Nausea
  • Vomiting
  • Gastrointestinal bleeding
  • Peptic ulcer
  • Anxiety
  • Drowsiness
  • Headache
  • Infertility in females
  • Pulmonary edema

Pregnancy & Lactation

  • FDA Pregnancy category: C
  • Avoidance during pregnancy and lactation unless benefits outweigh risks

Precautions & Warnings

  • Caution in patients over 65 years
  • Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, or liver dysfunction
  • Immediate discontinuation in case of corneal epithelial breakdown when using eye drops

Therapeutic Class

  • Used for Rheumatoid Arthritis
  • Non-Opioid Analgesics

Storage Conditions

  • Store in a dry place away from light and heat
  • Keep out of the reach of children

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