Giran-H 8 mg+12.5 mg (Tablet)
Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Candesartan cilexetil hydrochlorothiazide |
| Company | Aristopharma ltd |
Indications
- Treatment of hypertension
- Congestive heart failure
Pharmacology
- Combination of angiotensin II receptor blocker and diuretic
- Candesartan Cilexetil-Hydrochlorothiazide combination
- Mechanism of action of Candesartan Cilexetil
- Mechanism of action of Hydrochlorothiazide
- Effects on vasoconstriction and aldosterone secretion
- Renal tubular mechanisms of electrolyte reabsorption
- Plasma volume reduction and increase in plasma renin activity
- Renin-aldosterone link mediation by angiotensin II
Dosage & Administration
- Usual dose of one tablet once daily
Interaction
- No significant drug interactions reported
- Potential interactions with alcohol, barbiturates, narcotics, antidiabetic drugs, other antihypertensive drugs, skeletal muscle relaxants, tubocurarine, NSAIDs
Contraindications
- Hypersensitivity to any component of the product
- Hydrochlorothiazide contraindicated in patients with anuria or hypersensitivity to sulfonamide-derived drugs
Side Effects
- Mild and transient adverse events
- Comparable overall incidence to placebo
- Common side effects include headache, upper respiratory tract infection, back pain, influenza-like symptoms
Pregnancy & Lactation
- Not recommended for use during pregnancy and lactation
Precautions & Warnings
- No clinically significant effect on serum potassium levels
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
Therapeutic Class
- Combined antihypertensive preparations