Zolat 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 5.00 (10 x 10: ৳ 500.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Omeprazole
Company Al madina pharmaceuticals ltd
Also available as
Zolat 40 mg capsule

Indications

  • Treatment of gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer treatment
  • Prophylaxis in patients with a history of NSAID-associated ulcers
  • Gastro-esophageal reflux disease treatment
  • Long-term management of acid reflux disease
  • Treatment of acid-related dyspepsia
  • Treatment of severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome treatment
  • Helicobacter pylori-induced peptic ulcer treatment

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of antisecretory effect within one hour
  • Maximum effect within two hours
  • Inhibition of secretion lasts up to 72 hours

Dosage

  • Dosage for benign gastric and duodenal ulcer
  • Dosage for NSAID-associated duodenal or gastric ulcer
  • Gastro-esophageal reflux disease dosage
  • Long-term management of acid reflux disease dosage
  • Acid-related dyspepsia dosage
  • Prophylaxis of acid aspiration dosage
  • Zollinger-Ellison syndrome dosage
  • Helicobacter pylori eradication regimen dosage
  • Pediatric use in severe ulcerating reflux esophagitis dosage
  • IV Injection dosage

Administration

  • Direction for use of IV Injection
  • Direction for use of IV Infusion

Interaction

  • Impact on the absorption of ketoconazole
  • Metabolism through cytochrome P450
  • Potential delay in the elimination of diazepam, phenytoin, and warfarin
  • Monitoring of patients receiving warfarin or phenytoin
  • Plasma concentration changes during concomitant administration

Contraindications

  • Known hypersensitivity to omeprazole
  • Suspected gastric ulcer with possibility of malignancy

Side Effects

  • Skin rash, urticaria, and pruritus
  • Photosensitivity, bullous eruption, and erythema multiforme
  • Diarrhea and headache
  • Gastrointestinal reactions like constipation, nausea/vomiting, flatulence, and abdominal pain
  • Other reactions like dry mouth, stomatitis, candidiasis, paraesthesia, dizziness, and somnolence

Pregnancy & Lactation

  • No adverse effects of omeprazole on pregnancy or fetus/newborn child
  • Use during pregnancy
  • No information available on passage into breast milk
  • Discontinuation of breastfeeding if essential

Precautions & Warnings

  • Avoid concomitant use of clopidogrel and omeprazole
  • Observation of increased risk for osteoporosis-related fractures
  • Atrophic gastritis noted in long-term treatment
  • Concomitant use with methotrexate may lead to toxicities

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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