Primocef 750 mg/vial (IM/IV Injection)
750 mg vial: ৳ 125.37
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil |
| Company | Novo healthcare and pharma ltd |
| Also available as |
Title
- Primocef
- Cefuroxime Tablets
- Cefuroxime Suspension
Categories
- Antibiotics
- Pharmaceuticals
- Infectious Disease Treatments
Description
- Primocef is indicated for the treatment of infections caused by sensitive bacteria, with a broad spectrum of bactericidal activity.
- Cefuroxime is a well-characterized and effective antibacterial agent, with good stability to bacterial β-lactamase, and consequently, is active against many ampicillin-resistant and amoxycillin-resistant strains.
Dimensions
- Various tablet and suspension sizes available for different age groups such as adolescents, adults, and pediatric patients.
Color options
- N/A
Functions
- Treats Pharyngitis/Tonsillitis, Acute Bacterial Otitis Media, Acute bacterial maxillary sinusitis, Lower respiratory tract infections, Skin and skin-structure infections, Urinary tract infections, Bone and Joint Infections, Gonorrhoea, and Early Lyme Disease (erythema migrans).
Materials
- Active ingredient: Cefuroxime
- Inactive ingredients in tablets and suspension.
Technical specifications
- Broad-spectrum bactericidal activity against a wide range of common pathogens, including β-lactamase producing strains.
- Stability to bacterial β-lactamase, active against many ampicillin-resistant and amoxycillin-resistant strains.
Design elements
- Variety of dosage forms including tablets, suspension, and parenteral administration.
Usability features
- Freshly reconstituted solution recommended for administration.
Dosage information
- Detailed dosage information for adolescents, adults, pediatric patients, and special cases such as pneumonia, gonorrhoea, meningitis, and surgical prophylaxis.
Administration information
- Recommendation for the use of freshly reconstituted solution.
Interaction information
- No potentially hazardous interactions reported.
Contraindications
- Cefuroxime is contraindicated in patients with known allergy to Cephalosporins.
Side effects
- Adverse effects to Primocef are generally mild and transient, including rashes and gastrointestinal disturbances. Prolonged use may result in the overgrowth of non-susceptible organisms.
Pregnancy and lactation
- US FDA pregnancy category of Cefuroxime is B.
- No adequate and well-controlled studies in pregnant women, caution advised during pregnancy and lactation.
Precautions and warnings
- Careful use in patients receiving concurrent treatment with potent diuretics and those with a history of colitis.
- Cephalosporin antibiotics may be given safely to patients who are hypersensitive to penicillin, although cross reactions have been reported.
Therapeutic class
- Second generation Cephalosporins
Reconstitution instructions
- Clear instructions for reconstitution for intramuscular and intravenous injections.
Storage conditions
- Store in a cool, dry place (below 30<sup>o</sup> C), away from light and moisture. Keep out of the reach of children.
Other attributes
- No potentially hazardous interactions reported.
- Animal reproduction studies are not always predictive of human response.
- Primocef has shown to be not likely to pose a problem at the recommended dose levels.