Primocef 1.5 gm/vial (IV Injection)
1.5 gm vial: ৳ 200.60
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil |
| Company | Novo healthcare and pharma ltd |
| Also available as |
Title
Primocef
Categories
- Medicine
- Antibiotic
Description
Primocef is indicated for the treatment of infections caused by sensitive bacteria. Its pharmacology includes broad-spectrum bactericidal activity against common pathogens, including beta-lactamase producing strains. It has good stability to bacterial beta-lactamase and is active against many ampicillin-resistant and amoxycillin-resistant strains.
Dimensions
N/A
Color Options
- N/A
Functions
- Treatment of infections caused by sensitive bacteria
- Broad-spectrum bactericidal activity
Materials
- Cefuroxime
- Water for injection
Technical Specifications
- Dosage:
- Tablet or Suspension:
- Adolescents and Adults (13 years and older):
- Pharyngitis/Tonsillitis: 250 mg b.i.d. for 5-10 days
- Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
- Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days
- ...and more
- Paediatric Patients (3 months to 12 years):
- Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
- Acute otitis media: 30 mg/kg/day b.i.d for 10 days
- Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days
- Impetigo: 30 mg/kg/day b.i.d for 10 days
- Parenteral:
- Adult: 750 mg three times daily by IM or IV injection
- Children (above 3 months of age): 30 - 100 mg/kg/day given in 3 or 4 equally divided doses
- Surgical prophylaxis: 1.5 gm by IV injection at induction of anaesthesia
- Pneumonia: 1.5 gm IV injection twice daily for 2-3 days, followed by 500 mg twice daily (oral) for 7-10 days
- and more
- Meningitis:
- Adult: 3 gm IV injection three times daily
- Children (above 3 months of age): 200-240 mg/kg/day by IV injection in 3 or 4 divided doses
- Bone and Joint Infections:
- Adult: 1.5 gm IV injection four times daily
- Children (above 3 months of age): 150 mg/kg/day in equally divided doses every 8 hours
- Adolescents and Adults (13 years and older):
- Tablet or Suspension:
Design Elements
- Cephalosporin antibiotics
Usability Features
- Administration: Recommended to use freshly reconstituted solution. Maintains potency for at least 24 hours at room temperature or 48 hours at 5°C
- Interaction: No potentially hazardous interactions reported
- Contraindications: Contraindicated in patients with known allergy to Cephalosporins
- Side Effects: Adverse effects occurred infrequently and have been generally mild and transient in nature. Prolonged use may result in the overgrowth of non-susceptible organisms
- Pregnancy & Lactation: Cefuroxime is US FDA pregnancy category B. Excreted in human milk, caution advised when administered to nursing women
- Precautions & Warnings: Should be given with care to patients receiving concurrent treatment with potent diuretics & who have a history of colitis. Cross reactions with penicillin have been reported, but not likely to be a problem at recommended dose levels
- Reconstitution:
- For 750 mg intramuscular injection: Add 3 ml water for injection to vial and then shake gently for dispersion
- For 750 mg intravenous injection: Add 8 ml water for injection to vial and then shake gently for dispersion. The solution should be slowly injected directly into a vein over a 3 to 5 minutes period
- For 1.5 g intravenous injection: Add 16 ml Water for injection to vial and then shake gently for dispersion. The solution should be slowly injected directly into a vein over a 3 to 5 minutes period
- Storage Conditions: Store in a cool, dry place (below 30°C), away from light & moisture. Keep out of the reach of children
Therapeutic Class
Second generation Cephalosporins