Arbitan Plus 75 mg+12.5 mg (Tablet)
Unit Price: ৳ 6.03 (3 x 10: ৳ 180.90)
Strip Price: ৳ 60.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Irbesartan hydrochlorothiazide |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Treatment of hypertension
- Initial therapy for patients needing multiple drugs
- Control of blood pressure goals
- Management of stage 2 hypertension
Pharmacology
- Blocks vasoconstrictor effects of angiotensin II
- Stimulates aldosterone synthesis
- Selective antagonist of AT1 receptors
- Thiazide diuretic effect on renal tubular mechanisms
Dosage & Administration
- Initial dose of Irbesartan 150 mg & Hydrochlorothiazide 12.5 mg orally once a day
- Maximum dose of Irbesartan 300 mg & Hydrochlorothiazide 25 mg orally once a day
Interaction
- Interacts with other antihypertensives
- Potential interactions with CNS depressants
- Impact on other medication effects
Contraindications
- Hypersensitivity to any component
- Anuria or hypersensitivity to sulfonamide-derived drugs
- Avoid coadministration with aliskiren in diabetes patients
Side Effects
- Hyperkalemia
- Chest pain
- Musculoskeletal pain
- Flu-like syndrome
- Edema
- Dizziness
- Orthostatic hypotension
- Anorexia
- Photosensitivity
- Anaphylaxis
Pregnancy & Lactation
- Category D in pregnancy
- Crosses the placenta
- Possible excretion in human milk
- Potential adverse effects on nursing infant
Precautions & Warnings
- Avoid in nursing
- Caution in lactation
- Dose adjustments for renal dysfunction
- Caution in liver dysfunction
Use in Special Populations
- No adjustment recommended for mild to moderate renal dysfunction
- Not recommended in severe renal dysfunction
Overdose Effects
- Hypotension and tachycardia manifestations
- No serum level determinations widely available
- Acute lethal doses in animal studies
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Store in cool and dry place