Arbitan Plus 150 mg+12.5 mg (Tablet)

Unit Price: ৳ 12.05 (3 x 10: ৳ 361.50)
Strip Price: ৳ 120.50

Medicine Details

Product Title

  • Irbesartan & Hydrochlorothiazide Tablet

Category

  • Medicine
  • Antihypertensive

Indications

  • Treatment of hypertension
  • Initial therapy for hypertension
  • Stage 2 hypertension treatment

Pharmacology

  • Irbesartan blocks vasoconstrictor effects of angiotensin II
  • Hydrochlorothiazide is a thiazide diuretic

Dosage & Administration

  • Initial dose: Irbesartan 150mg & Hydrochlorothiazide 12.5mg once a day
  • Add-on/Replacement therapy: Irbesartan 150-300mg & Hydrochlorothiazide 12.5-25mg once a day
  • Maximum dose: Irbesartan 300mg & Hydrochlorothiazide 25mg once a day

Interactions

  • Other antihypertensives
  • CNS depressants
  • Antidiabetics
  • NSAIDs
  • Alcohol
  • Digitalis glycosides

Contraindications

  • Hypersensitivity to any component
  • Anuria
  • Hypersensitivity to sulfonamide-derived drugs
  • Concomitant use with aliskiren in diabetes

Side Effects

  • Hyperkalemia
  • Chest pain
  • Tachycardia
  • Anorexia
  • Hypotension
  • Dizziness
  • Headache
  • Photosensitivity

Pregnancy & Lactation

  • Pregnancy Category D
  • Discontinue use during pregnancy
  • Thiazides cross placenta
  • Thiazides appear in human milk
  • Consideration for nursing mothers

Precautions & Warnings

  • Caution in child nursing
  • Consideration for lactation

Use in Special Populations

  • Renal Dose Adjustments for mild to moderate renal dysfunction and severe renal dysfunction
  • Caution in liver dose adjustments

Overdose Effects

  • Manifestations: hypotension, tachycardia, electrolyte depletion
  • No established role of serum level determinations in management
  • Acute oral toxicity in rodents
  • LD50 in mice and rats

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Cool and dry place

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