Denixil 1 mg (Tablet)
Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Renata limited |
| Also available as |
ProductTitle
Denixil 1 mg Tablet
Categories
- Medicine
- Pharmaceuticals
- Benzodiazepines
Description
Denixil 1 mg Tablet is indicated for the treatment of panic disorder, with or without agoraphobia, and as an adjunct in the treatment of the Lennox-Gastaut Syndrome, akinetic and myoclonic seizures. It exhibits anticonvulsive, sedative, muscle relaxing, and anxiolytic effects through enhancement of the GABAergic neurotransmission.
Attributes
- Indications:
- Treatment of panic disorder with or without agoraphobia
- Treatment of Lennox-Gastaut Syndrome
- Adjunct in the treatment of seizures
- Pharmacology:
- Anticonvulsive effects
- Sedative effects
- Muscle relaxing effects
- Anxiolytic effects
- Enhancement of GABAergic neurotransmission
- Dosage & Administration:
- Adults initial dose not to exceed 1.5 mg/day
- Initial dose for panic disorder is 0.25 mg
- Pediatric dosage based on body weight
- Infants and children dosage
- Adults intravenous dosage
- Slow intravenous injection
- Intravenous infusion
- Intramuscular injection
- Interactions:
- No alteration of phenytoin, carbamazepine, or phenobarbital pharmacokinetics
- Effect on the metabolism of other drugs not investigated
- Contraindications:
- Hypersensitivity to benzodiazepines
- Clinical or biochemical evidence of significant liver disease
- Contradicted in acute narrow angle glaucoma
- Side Effects:
- CNS depression
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Aphonia
- Tremor
- Vertigo
- Depression
- Hallucinations
- Insomnia
- Palpitations
- Pregnancy & Lactation:
- Potential for producing congenital malformations
- Acts as a teratogen
- Administered to pregnant women only if benefits outweigh risks
- Drug passes into maternal milk in small amounts
- Breastfeeding should be discontinued if administering Denixil
- Precautions & Warnings:
- May increase incidence or precipitate onset of generalized tonic-clonic seizures
- Concomitant use with valproic acid may produce absence status
- Special attention in patients with several types of seizure disorders
- Use in Special Populations:
- Increased production of saliva and bronchial secretion in infants and small children
- Greater pharmacologic effects in elderly patients
- No dose adjustment required in renal impairment
- Reduced clearance in liver cirrhosis
- Overdose Effects:
- Drowsiness
- Ataxia
- Dysarthria
- Areflexia
- Apnoea
- Hypotension
- Cardiorespiratory depression
- Monitor vital signs and institute supportive measures
- Prevent further absorption using activated charcoal
- Therapeutic Class:
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
- Reconstitution:
- Dilution with water for intravenous administration
- Preparation of injection solution
- Dilution ratio for intravenous infusion
- Stability of diluting media
- Use of PVC infusion bags for infusing Denixil
- Appropriate method for prevention of further absorption
- Storage Conditions:
- Keep in a dry place away from light and heat
- Keep out of the reach of children
- Chemical Structure:
- Molecular Formula: C15H10ClN3O3
- Commonly Asked Questions:
- Sleeping pill usage
- Longer-term usage
- Withdrawal symptoms
- Early symptoms of suicidal thoughts
- Weight gain
- Effect on memory
- Overdose symptoms
- Drug interactions
- Quick Tips:
- High addiction potential
- Caution while driving or performing activities requiring mental focus
- Avoid alcohol consumption
- Inform doctor about pregnancy or breastfeeding
- Do not stop suddenly without doctor's advice