Bisoren M 2.5 mg+5 mg (Tablet)
Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Bisoprolol fumarate amlodipine besilate |
| Company | Renata limited |
Indications
- Treatment of hypertension
Pharmacology
- Dihydropyridine calcium antagonist
- Cardioselective adrenoceptor blocking agent
- Inhibition of transmembrane influx of calcium ions into vascular and cardiac muscle
- Reduction in peripheral vascular resistance
- Reduction in blood pressure
Dosage & Administration
- One tablet once daily
Interactions
- Not recommended combinations with verapamil and diltiazem type of drugs
- Caution with strong or moderate CYP3A4 inhibitors and inducers
- Combinations to be considered with mefloquine, rifampicin, ergotamine derivatives, MAO inhibitors
Contraindications
- Acute heart failure or during episodes of heart failure decompensation
- Obstruction of the outflow tract of the left ventricle
- Cardiogenic shock
- Second or third degree AV block
- Sick sinus syndrome
- Untreated phaeochromocytoma
- Hypersensitivity to bisoprolol, amlodipine, or excipients
Side Effects
- Common: Dizziness, headache, somnolence, palpitations, edema, fatigue
- Uncommon: Insomnia, mood changes, visual disturbances, dyspnea, skin discoloration, myalgia
- Rare: Allergic reactions, nightmares, hallucinations, increased liver enzymes
Pregnancy & Lactation
- Not recommended
Precautions & Warnings
- Caution in patients with heart failure, impaired hepatic function, and obstructive airways diseases
- Avoid in patients with certain conditions like severe bronchial asthma, diabetes mellitus, and psoriasis
- Careful use in patients undergoing general anesthesia
Use in Special Populations
- Usual doses can be administered to elderly people with caution
- Pediatric use not established
- Special caution in patients with liver or kidney disease
Overdose Effects
- Possible signs of overdose include bradycardia, hypotension, bronchospasm, and hypoglycemia
Therapeutic Class
- Anti-hypertensive
Storage Conditions
- Keep in a dry place below 30°C
- Protect from light
- Keep out of the reach of children