Comarit 80 mg (Capsule)
Unit Price: ৳ 2,200.00 (7 x 4: ৳ 61,600.00)
Strip Price: ৳ 8,800.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cabozantinib |
| Company | Genvio pharma ltd |
| Also available as |
Indications
- Renal Cell Carcinoma
- Hepatocellular Carcinoma
Pharmacology
- Inhibition of tyrosine kinase activity of multiple receptors
- Absorption time
- Distribution volume
- Protein binding
- Elimination half-life
- Metabolism details
- Excretion pathways
Dosage & Administration
- Recommended dosage for RCC
- Recommended dosage for HCC
- Dosage instructions for pediatric use
- Dosage modifications for hepatic impairment
- Dosage modifications for CYP450 inhibitors/inducers
- Administration guidelines
Interaction
- Interaction with strong CYP3A4 inhibitors
- Interaction with strong CYP3A4 inducers
- Avoidance of grapefruit and St. John's Wort
Contraindications
- Hypersensitivity to Cabozantinib or its components
Side Effects
- Hemorrhage
- Perforations and Fistulas
- Thrombotic Events
- Hypertension and Hypertensive Crisis
- Diarrhea
- Palmar-plantar Erythrodysesthesia
- Proteinuria
- Osteonecrosis of the Jaw
- Wound Complications
- Reversible Posterior Leukoencephalopathy Syndrome
Pregnancy & Lactation
- Effects on pregnancy
- Effects on lactation
- Need for effective contraception
- Impact on fertility
Precautions & Warnings
- Severe hemorrhage
- Perforation and fistula management
- Risk of thrombotic events
- Management of hypertension
- Diarrhea management
- Palmar-Plantar Erythrodysesthesia management
- Proteinuria monitoring
- Osteonecrosis of the Jaw monitoring and management
- Wound complications management
- Reversible Posterior Leukoencephalopathy Syndrome evaluation
- Embryo-Fetal Toxicity precautions
Overdose Effects
- Reported case of overdose effects
Therapeutic Class
- Tyrosine Kinase Inhibitor
Storage Conditions
- Storage temperature and environmental requirements