Cavazide 300 mg+12.5 mg (Tablet)
Unit Price: ৳ 24.00 (1 x 10: ৳ 240.00)
Strip Price: ৳ 240.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Irbesartan hydrochlorothiazide |
| Company | Unimed unihealth pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of hypertension
- Blood pressure control
- Initial therapy for hypertension
- Indicated for stage 2 hypertension
Pharmacology
- Blocks angiotensin II receptor
- Does not inhibit ACE or renin
- Thiazide diuretic
- Affects renal tubular mechanisms
Dosage & Administration
- Initial dose: Irbesartan 150 mg & Hydrochlorothiazide 12.5 mg
- Dose adjustment after 1 to 2 weeks
- Maximum dose: Irbesartan 300 mg & Hydrochlorothiazide 25 mg
Interactions
- Potential interactions with other antihypertensives
- Coadministration considerations with various medications
Contraindications
- Hypersensitivity to any component
- Contraindicated in patients with anuria
- Avoid coadministration with aliskiren in diabetic patients
Side Effects
- Irbesartan: Hyperkalemia, Chest pain, Musculoskeletal pain, Edema, Dizziness
- Hydrochlorothiazide: Anorexia, Hypotension, Photosensitivity, Hypokalemia
Pregnancy & Lactation
- Pregnancy Category D
- Risks of using during second and third trimesters
- Presence in human milk
- Adverse effects on nursing infant
Precautions & Warnings
- Caution during lactation
- Renal and liver dose adjustments
Use in Special Populations
- Renal dose adjustments for different levels of dysfunction
- Caution in liver dysfunction
Overdose Effects
- Manifestations of irbesartan and hydrochlorothiazide overdose
- Considerations in managing overdose
Therapeutic Class
- Belongs to combined antihypertensive preparations
Storage Conditions
- Cool and dry storage