Lenvika 4 mg (Capsule)
Unit Price: ৳ 700.00 (3 x 10: ৳ 21,000.00)
Strip Price: ৳ 7,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Lenvatinib mesylate |
| Company | Genvio pharma ltd |
| Also available as |
Indications
- Differentiated Thyroid Cancer
- Renal Cell Carcinoma
- Hepatocellular Carcinoma
- Endometrial Carcinoma
Pharmacology
- Kinase inhibitor
- Inhibits VEGF receptors
- Inhibits FGF receptors
- Antiproliferative activity in hepatocellular carcinoma cell lines
Absorption
Peak plasma concentration time
Distribution
- Binding to human plasma proteins
- Blood-to-plasma concentration ratio
Metabolism
- Enzymatic process
- Non-enzymatic process
- Excretion pathway
Elimination
Terminal elimination half-life
Dosage
- Dose reduction for renal/hepatic impairment
- Recommended dosages for different cancer types
Administration
Options for administration of capsules
Interaction
Potential drug interactions
Contraindications
Known hypersensitivity contraindication
Side Effects
- Hypertension
- Cardiac dysfunction
- Arterial thromboembolic events
- Hepatotoxicity
- Renal failure/impairment
- Diarrhea
- Fistula formation
- QT Interval Prolongation
- Hypocalcemia
- Reversible posterior leukoencephalopathy syndrome
- Hemorrhagic events
- Impairment of thyroid stimulating hormone suppression/thyroid dysfunction
- Wound healing complications
Pregnancy & Lactation
- Embryo-fetal harm risk
- Use in pregnancy precautions
- Use in lactation precautions
Precautions & Warnings
- Hypertension monitoring
- Cardiac dysfunction monitoring
- Arterial thromboembolic events precautions
- Hepatotoxicity monitoring
- Renal failure/impairment precautions
- Proteinuria monitoring
- Diarrhea management
- Fistula and Gastrointestinal Perforation precautions
- QT Interval Prolongation monitoring
- Hypocalcemia precautions
- Reversible Posterior Leukoencephalopathy Syndrome precautions
- Hemorrhagic Events precautions
- Impairment of Thyroid Stimulating Hormone Suppression precautions
- Wound Healing Complications precautions
Use in Special Populations
- Dosage modifications for severe renal impairment
- Dosage modifications for severe hepatic impairment
Overdose Effects
Expected effects of overdose
Storage Conditions
Guidelines for storage