Hemoject 500 mg/10 ml (IV Injection or Infusion)

10 ml vial: ৳ 700.00

Medicine Details

Category Details
Generic Ferric carboxymaltose
Company Nuvista pharma ltd
Also available as
Hemoject 1 gm injection

Indications

  • Treatment of iron deficiency anaemia in adult patients with intolerance to oral iron
  • Treatment of iron deficiency anaemia in adult patients with unsatisfactory response to oral iron
  • Treatment of iron deficiency anaemia in adult patients with non-dialysis dependent chronic kidney disease

Description

  • Colloidal iron (III) hydroxide in complex with Carboxymaltose, a Carbohydrate polymer that releases iron

Dosage & Administration

  • Stepwise approach for determination, calculation, and administration of individual iron need
  • Posology based on body weight and haemoglobin level
  • Maximum individual iron dose limitations
  • Post-iron repletion assessments

Interaction

  • Formal drug interaction studies not performed

Contraindications

  • Hypersensitivity to the active substance or any excipients
  • Serious hypersensitivity to other parenteral iron products
  • Anaemia not attributed to iron deficiency
  • Evidence of iron overload or disturbances in iron utilization

Side Effects

  • Infrequent and mild side effects
  • Common side effects: nausea, headache, dizziness, hypertension, injection site reactions
  • Uncommon side effects: dysgeusia, tachycardia, hypotension, dyspnoea, abdominal pain
  • Rare side effects: anaphylactoid reactions, loss of consciousness, anxiety, phlebitis

Pregnancy & Lactation

  • No adequate and well-controlled trials in pregnant women
  • Animal data suggesting potential influence on fetal skeletal development
  • Restricted use during second and third trimester if benefit outweighs potential risk
  • Unlikely risk to breast-fed child based on limited data

Precautions & Warnings

  • Risk of serious hypersensitivity reactions
  • Monitoring for signs and symptoms of hypersensitivity during and after administration
  • Potential transient elevations in systolic blood pressure
  • Laboratory test alterations in the 24 hours following administration

Use in Special Populations

  • Maximum daily injection dose limitations for patients with haemodialysis-dependent chronic kidney disease
  • Not recommended in children under 14 years

Overdose Effects

  • Potential accumulation of iron leading to hemosiderosis
  • Monitoring of iron parameters such as serum ferritin and transferrin saturation
  • Consideration of iron chelator use if iron accumulation has occurred

Therapeutic Class

  • Parenteral Iron Preparations

Storage Conditions

  • Store in a cool and dry place below 30°C
  • Keep away from light and do not freeze
  • Keep out of the reach of children

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