Predimax 5 mg (Tablet)

Unit Price: ৳ 1.72 (20 x 10: ৳ 344.00)
Strip Price: ৳ 17.20

Medicine Details

Category Details
Generic Prednisolone
Company Acme laboratories ltd
Also available as
Predimax 10 mg tablet Predimax 20 mg tablet

Indications

  • Rheumatic Disorders
  • Endocrine Disorders
  • Dermatologic Diseases
  • Allergic States
  • Respiratory Diseases
  • Hematologic Disorders
  • Edematous States
  • Gastrointestinal Diseases

Pharmacology

Synthetic adrenocortical drug with predominantly glucocorticoid properties, inhibits the action of the Phospholipase A2 enzyme, well absorbed from the GI tract, 70-90% protein-bound in the plasma, metabolized mainly in the liver, excreted in the urine

DosageAdministration

  • Adult:
    • Nephrotic Syndrome: Initial dose 2 mg/kg/day, maximum 80 mg/day, Maintenance dose 0.5-1 mg/kg every other day
    • Anti-inflammatory: 5-60 mg per day
    • Acute Asthma: 40-60 mg/day in single daily dose or divided q12 hr for 3-10 days
  • Pediatric:
    • Asthma: Varies by age group
    • Anti-inflammatory: 0.05-2 mg/kg/day
    • Immunosuppression: 0.05-2 mg/kg/day

Interaction

  • Reduced efficacy with Aminoglutethimide, Antacids, Barbiturates, Carbamazepine, Mitotane, Rifampin
  • Reduces blood potassium levels
  • Digitalis can cause cardiac arrhythmias if hypokalemia occurs
  • Immunization should be done carefully

Contraindications

Systemic infections, hypersensitivity to any ingredient, ocular herpes simplex

SideEffects

  • Increased appetite
  • Indigestion
  • Nervousness or restlessness
  • Skin color changes
  • Dizziness or lightheadedness
  • Flushing of face or cheeks
  • Hiccups
  • Increased sweating
  • Sensation of spinning

PregnancyLactation

Not recommended during pregnancy unless essential, may appear in breast milk

PrecautionsWarnings

  • Diabetes
  • Hypertension
  • Psychological disturbances
  • Osteoporosis
  • Pregnancy
  • Chronic nephritis

OverdoseEffects

Adverse effects develop after prolonged use of excessive doses, treatment is symptomatic with gradual dose reduction

TherapeuticClass

Glucocorticoids

StorageConditions

Store in a cool and dry place, protected from light, keep out of reach of children

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