Glipita M XR 50 mg+1000 mg (Tablet (Extended Release))

Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)

Strip Price: ৳ 200.00

Medicine Details

Category	Details
Generic	Sitagliptin metformin hydrochloride
Company	Beximco pharmaceuticals ltd
Also available as	Glipita m 50 mg tablet Glipita m 50 mg tablet Glipita m xr 50 mg tablet

Indications

Adjunct to diet and exercise for type 2 diabetes mellitus
Improving glycemic control
Type 1 diabetes not suitable for treatment
Limitations in pancreatitis history

Pharmacology

Combines two antihyperglycemic agents
Complementary mechanisms of action
Dipeptidyl peptidase-4 (DPP-4) inhibitor
Biguanide class member

Dosage & Administration

Individualized dosage
Maximum recommended daily dose
Twice daily administration with meals
Gradual dose escalation
Starting dose based on patient's current regimen
Extended-release tablet dosing

Interaction

Cationic drugs caution
Phenprocoumon interaction
Levothyroxine interaction

Contraindications

Renal disease
Metabolic acidosis
Serious hypersensitivity reaction
Radiologic studies caution

Side Effects

Common adverse reactions
Diarrhea
Upper respiratory tract infection
Headache
Hypoglycemia
Nasopharyngitis
Nausea/vomiting
Fatulence

Pregnancy & Lactation

Pregnancy Category B
Limited safety information in pregnant women
Excretion in human milk caution

Precautions & Warnings

Lactic Acidosis risk factors
Hepatic disease caution
Renal function assessment
Postmarketing reports
Monitoring of vitamin B12 level
Hematologic parameters monitoring

Overdose Effects

Supportive measures for overdose
Dialyzable nature of Sitagliptin
Hemodialysis for metformin overdosage
Pancreatitis risk

Therapeutic Class

Combination Oral hypoglycemic preparations

Storage Conditions

Storage temperature below 25°C
Dry and away from light
Keep out of reach of children
Expiry date concern
Dispensed on prescription

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