Unifav 200 mg (Tablet)

Unit Price: ৳ 200.00 (3 x 10: ৳ 6,000.00)
Strip Price: ৳ 2,000.00

Medicine Details

Indications

  • Treatment of novel or re-emerging pandemic influenza virus infections (limited to cases in which other influenza antiviral drugs are ineffective or not sufficiently effective)

Description

  • Approved for manufacture and sale in Japan as an influenza antiviral
  • Selective inhibition of the RNA polymerase of the influenza virus
  • Effective in treating COVID-19 during outbreaks of novel or re-emerging influenza virus infections
  • Production and distribution at the discretion of Japan’s Health, Labor and Welfare Ministry

Pharmacology

  • Metabolized into favipiravir ribosyl triphosphate (favipiravir RTP)
  • Selectively inhibits RNA polymerase of the influenza virus
  • Effective against all types and sub-types of human influenza A, B, and C viruses in vitro

Dosage & Administration

  • Usual adult dosage: 1600 mg of Favipiravir administered orally twice daily on Day 1, followed by 600 mg orally twice daily from Day 2 to Day 5
  • Total treatment duration should be 5 days

Interaction

  • In animal studies: decreased RBC production, increased liver function parameters such as AST, ALP, ALT, and total bilirubin
  • Toxicity information regarding Unifav in humans is not readily available

Contraindications

  • Contraindicated for pregnant women and women who may possibly be pregnant

Side Effects

  • Most common side effects: diarrhea and increase of blood uric acid levels

Pregnancy & Lactation

  • May cause delayed development or death of embryos during the early stage of pregnancy
  • Should not be given during pregnancy

Precautions & Warnings

  • Not to be given in pregnant women
  • Confirmation of non-pregnancy in women of childbearing potential before use
  • Thorough contraception measures from the start of the treatment to 7 days after the end of the treatment
  • Caution should be taken for Hepatic and renal impaired patients or use Unifav as per the direction of registered Physician

Use in Special Populations

  • Approved as an experimental drug, further studies needed about efficacy, toxic reactions, and use in children

Overdose Effects

  • In animal studies: decreased RBC production, increased liver function parameters such as AST, ALP, ALT, and total bilirubin
  • Toxicity information regarding Unifav in humans is not readily available

Therapeutic Class

  • Anti-viral drugs

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

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