Oxaban 10 mg (Tablet)
Unit Price: ৳ 25.00 (2 x 10: ৳ 500.00)
Strip Price: ৳ 250.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rivaroxaban |
| Company | Unimed unihealth pharmaceuticals ltd |
Indications
- Prevention of atherothrombotic events in adult patients after an Acute Coronary Syndrome (ACS) with elevated cardiac biomarkers
- Reduction in the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation
- Treatment of Deep vein thrombosis (DVT) & pulmonary embolism (PE)
- Prophylaxis of DVT in patients undergoing knee or hip replacement surgery
Pharmacology
Highly selective direct factor Xa inhibitor. Interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade
Dosage & Administration
- Recommended dose of 2.5 mg twice daily for specific conditions
- Different dosage for Nonvalvular Atrial Fibrillation based on Creatinin Clearance
- Variety of dosages for the treatment and prevention of DVT and PE
- May be taken with or without food
Interaction
Concomitant use with drugs that are combined P-gp and CYP3A4 inhibitors should be avoided
Contraindications
- Known hypersensitivity of Rivaroxaban or any of the excipients
- Active pathological bleeding
Side Effects
- Increased chance of bleeding
- Spinal or epidural hematoma
- Increased risk of stroke after discontinuation in nonvalvular atrial fibrillation
Pregnancy & Lactation
Pregnancy category C drug. Safety and efficacy in pregnant or breastfeeding women has not been established
Precautions & Warnings
- Early discontinuation increases the risk of thrombotic events
- Risk of fatal bleeding in the presence of certain risk factors
- Monitoring for signs or symptoms of neurological impairment
Overdose Effects
- May lead to hemorrhage
- Specific antidote not available
- Limited absorption at single doses >50 mg
Therapeutic Class
Oral Anti-coagulants
Storage Conditions
Cool (below 30°C) & dry place protected from light