Oxaban 10 mg (Tablet)

Unit Price: ৳ 25.00 (2 x 10: ৳ 500.00)
Strip Price: ৳ 250.00

Medicine Details

Indications

  • Prevention of atherothrombotic events in adult patients after an Acute Coronary Syndrome (ACS) with elevated cardiac biomarkers
  • Reduction in the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation
  • Treatment of Deep vein thrombosis (DVT) & pulmonary embolism (PE)
  • Prophylaxis of DVT in patients undergoing knee or hip replacement surgery

Pharmacology

Highly selective direct factor Xa inhibitor. Interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade

Dosage & Administration

  • Recommended dose of 2.5 mg twice daily for specific conditions
  • Different dosage for Nonvalvular Atrial Fibrillation based on Creatinin Clearance
  • Variety of dosages for the treatment and prevention of DVT and PE
  • May be taken with or without food

Interaction

Concomitant use with drugs that are combined P-gp and CYP3A4 inhibitors should be avoided

Contraindications

  • Known hypersensitivity of Rivaroxaban or any of the excipients
  • Active pathological bleeding

Side Effects

  • Increased chance of bleeding
  • Spinal or epidural hematoma
  • Increased risk of stroke after discontinuation in nonvalvular atrial fibrillation

Pregnancy & Lactation

Pregnancy category C drug. Safety and efficacy in pregnant or breastfeeding women has not been established

Precautions & Warnings

  • Early discontinuation increases the risk of thrombotic events
  • Risk of fatal bleeding in the presence of certain risk factors
  • Monitoring for signs or symptoms of neurological impairment

Overdose Effects

  • May lead to hemorrhage
  • Specific antidote not available
  • Limited absorption at single doses >50 mg

Therapeutic Class

Oral Anti-coagulants

Storage Conditions

Cool (below 30°C) & dry place protected from light

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