Afexa 180 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fexofenadine hydrochloride |
| Company | Unimed unihealth pharmaceuticals ltd |
| Also available as |
Title
- Afexa 180 mg Tablet
Therapeutic Class
- Non-sedating antihistamines
Indications
- Relief of symptoms associated with seasonal and perennial allergic rhinitis
- Relief of symptoms associated with chronic idiopathic urticaria
Pharmacology
- Binds to and stabilizes the inactive form of the H1 receptor
- Prevents activation and downstream effects of histamine binding
- Potent and selective affinity for H1 receptors
- No evidence of antidopaminergic, antiserotonergic, anticholinergic, sedative, or adrenergic blocking activity
- Does not cross the blood-brain barrier
Dosage & Administration
- Adults and children 12 years and older: 60 mg twice daily or 120 mg once daily or 180 mg once daily for allergic rhinitis
- Adults and children 12 years and older: 60 mg twice daily or 120 mg once daily or 180 mg once daily for chronic idiopathic urticaria
Interaction
- No hepatic biotransformation
- Increased plasma levels when coadministered with erythromycin or ketoconazole
- No interaction observed with omeprazole
- Reduction in bioavailability when administered with antacids containing aluminium and magnesium hydroxide
Contraindications
- Known hypersensitivity to Fexofenadine Hydrochloride or any of its ingredients
Side Effects
- Common: headache, drowsiness, dizziness, nausea
- Uncommon: fatigue
- Hypersensitivity reactions, tachycardia, palpitations, diarrhea, rash, urticaria, pruritus
Pregnancy & Lactation
- Limited data in pregnant women, not recommended unless clearly necessary
- Fexofenadine was found to cross into human breast milk
Precautions & Warnings
- Limited data in older people, renally or hepatically impaired patients
- Administered with caution in these special groups
- Association with adverse reactions like tachycardia and palpitations
- Unlikely to produce significant effects on the ability to drive or use machines
- Suggested to check individual response before driving or performing complicated tasks
Use in Special Populations
- Altered pharmacokinetics in individuals with renal impairment
- Altered pharmacokinetics in individuals over 65 years of age
- Moderate to severe hepatic disease does not substantially affect the pharmacokinetics
Overdose Effects
- Reported effects of dizziness, drowsiness, fatigue, dry mouth
- No development of clinically significant adverse reactions at certain doses
- Maximum tolerated dose not established
- Symptomatic and supportive treatment recommended
- Haemodialysis does not effectively remove from blood
Mode of Action
- Binds to and stabilizes the inactive form of the H1 receptor
- Prevents activation and downstream effects of histamine binding
- Potent and selective affinity for H1 receptors
- No evidence of antidopaminergic, antiserotonergic, anticholinergic, sedative, or adrenergic blocking activity
- Does not cross the blood-brain barrier
Common Questions
- What is Afexa 180 mg Tablet?
- What are the uses of Afexa 180 mg Tablet?
- What are the Side Effects of Afexa 180 mg Tablet?
- What are the instructions for storage and disposal Afexa 180 mg Tablet?
- Can Afexa 180 mg Tablet make you sleepy?
- Can you overdose on Afexa 180 mg Tablet?
- How quickly does Afexa 180 mg Tablet work?
- Does Afexa 180 mg Tablet relieve symptoms of outdoor and indoor allergies?
- How to cope with dizziness caused by Afexa 180 mg Tablet?
- Can I take antacids while taking Afexa 180 mg Tablet?
- How should I take Afexa 180 mg Tablet?
- Is there any food or drink that I need to avoid while taking Afexa 180 mg Tablet?
- Can Afexa 180 mg Tablet cause heart problems?
- Quick Tips
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Compound Summary
- Molecular Formula: C32H39NO4
- Chemical Structure: [Chemical Structure Image]