Delight 20000 IU (Capsule)

Unit Price: ৳ 20.00 (2 x 10: ৳ 400.00)
Strip Price: ৳ 200.00

Medicine Details

Category Details
Generic Cholecalciferol vitamin d3
Company Opsonin pharma ltd
Also available as
Delight 40000 iu capsule Delight 2000 iu tablet Delight 200000 iu injectable solution oral im Delight 1000 iu tablet Delight 50000 iu capsule Delight 10000 iu oral solution

Title and Categories

  • Vitamin D3 Supplement
  • Vitamin-D preparations
  • Bone Health
  • Vitamin Supplement

Indications

  • Treatment of Vitamin D3 deficiency
  • Prevention of Vitamin D3 deficiency
  • Support for healthy bones and teeth
  • Immune system support
  • Prevention of rickets, osteomalacia, and osteoporosis
  • Prevention of pre-eclampsia during pregnancy
  • Promotion of healthy infant growth

Pharmacology

  • Active form: Calcitriol
  • Binds to Vitamin D receptors (VDRs)
  • Fat-soluble with a half-life of about 50 days
  • Absorbed in the small intestine
  • Metabolized to 25-hydroxy Vitamin D3 (Calcidiol) in the liver
  • Second hydroxylation to 1,25-dihydroxy Vitamin D3 (Calcitriol) occurs in the kidney
  • Increases calcium absorption

Dosage and Administration

  • Adult dosage: 40000 IU once weekly for 7 weeks for deficiency treatment
  • Adult maintenance therapy: 1400-2000 IU/day
  • Children (12-18 years) dosage for deficiency treatment: 20000 IU once every 2 weeks for 6 weeks
  • Infant and child syrup dosage for Cholecalciferol deficiency
  • Various dosage forms: capsule, film-coated tablet, oroflash/chewable tablets, syrup, injection

Interaction

  • Drugs causing Vitamin D3 deficiencies
  • Interaction with Magnesium containing Antacids, Digoxin, Thiazide Diuretics, Cholestyramine, Cholistipol, Phenytoin, Phenobarbital, Orlistat, Mineral Oil, Corticosteroids

Contraindications

  • Contraindicated in diseases associated with hypercalcemia
  • Known hypersensitivity to Vitamin D3 or its class
  • Evidence of Vitamin D3 toxicity

Side Effects

  • Rare symptoms include anorexia, lassitude, nausea & vomiting, diarrhea, constipation, weight loss, polyuria, sweating, headache, thirst, vertigo
  • Raised concentrations of calcium and phosphate in plasma and urine

Pregnancy and Lactation

  • Safe use up to 4000 IU during pregnancy
  • Recommended daily intake for pregnant women: 400 IU
  • Vitamin D3 and its metabolites excreted in breast milk
  • No observed overdose in breastfed infants
  • Prescribing consideration for breast-fed child

Precautions and Warnings

  • Plasma-calcium concentration monitoring for patients on high doses
  • Consultation for patients using Digoxin and Thiazide Diuretics
  • Consultation for patients with liver or kidney disease, primary hyperthyroidism, lymphoma, tuberculosis, and granulomatous disease

Use in Special Populations

  • Safety & efficacy not established in children under 12 years

Overdose Effects

  • Hypervitaminosis D

Therapeutic Class

  • Vitamin in bone formation
  • Vitamin-D preparations

Storage Conditions

  • Store below 30°C temperature
  • Protect from light & moisture
  • Keep out of the reach of children

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