Oromax 2% w/w (Oral Gel)
15 gm tube: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Miconazole nitrate |
| Company | The white horse pharmaceuticals ltd |
Indications
- For the treatment of oral and gastrointestinal candidiasis
- For eradication of fungal colonization in the mouth and gastrointestinal tract
- For the treatment of super infections due to gram-positive bacteria
- Treatment of dermatomycoses such as Tinea pedis, Tinea corporis, Tinea manuum, etc.
- Alleviating effect on the pruritis which frequently accompanies infection
- Rapid relief of symptoms
- Infections of the skin (e.g. intertrigo)
- Perianal infections
- Stomatitis angularis (cheilitis)
- Balanoposthitis
- Otitis externa
Pharmacology
- Antifungal activity against dermatophytes and yeasts
- Antibacterial activity against certain gram-positive bacilli and cocci
- Inhibition of demethylation step in ergosterol biosynthesis
- Disruption in production of ergosterol disrupts fungal cell membrane
- Systemic absorption after oral gel administration
- Plasma protein binding
- Metabolism of absorbed Miconazole
- Excretion in urine
- Terminal plasma half-life
- Pharmacokinetics in renal impaired patients
Dosage
- Dosage for oropharyngeal candidosis in infants and adults
- Dosage for gastrointestinal tract candidosis in infants, children, and adults
- Missed dose instructions
- Application of Miconazole Cream for various conditions
- Duration of treatment for different conditions
Administration
- Application frequency for localized mouth lesions
- Duration of treatment
- Removal of dental prosthesis for oral candidosis
- Application to affected area
- Optimal contact with affected area
Interaction
- Concomitant treatment with specific drugs to be avoided
- Potential delay in metabolism and resulting toxicity
Contraindications
- Known hypersensitivity to the active ingredient
Side Effects
- Nausea and vomiting
- Diarrhea with long term use
- Allergic reactions
Pregnancy & Lactation
- No safety information during pregnancy
- Caution in nursing women
Precautions & Warnings
- Monitoring anti-coagulant effect
- Monitoring phenytoin plasma levels
- Caution in infants and young children
Overdose Effects
- Vomiting and diarrhea
- Symptomatic and supportive treatment
Therapeutic Class
- Aural Anti-fungal preparations
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children