Terbitac 250 mg (Tablet)

Unit Price: ৳ 50.00 (1 x 10: ৳ 500.00)
Strip Price: ৳ 500.00

Medicine Details

Category Details
Generic Terbinafine hydrochloride
Company Ziska pharmaceuticals ltd
Also available as

Indications

  • Treatment of onychomycosis of the toenail
  • Treatment of onychomycosis of the fingernail
  • Treatment of Tinea Capitis
  • Treatment of fungal infection of the skin
  • Treatment of yeast infections of the skin
  • Treatment of Pityriasis (tinea) versicolor

Pharmacology

  • Inhibition of biosynthesis of Ergosterol
  • Fungicidal activity
  • Inhibition of Squalene Epoxidase enzyme

Dosage & Administration

  • Dosage for fingernail onychomycosis
  • Dosage for toenail onychomycosis
  • Body Weight-based dosage for granules
  • Duration of treatment for various infections
  • Application frequency and duration for cream and spray
  • Instructions for cleansing and drying affected areas before application

Interaction

  • Inhibition of CYP450 2D6 isozyme
  • Drugs metabolized by CYP450 2D6 isozyme

Contraindications

  • Hypersensitivity to terbinafine

Side Effects

  • Gastrointestinal symptoms
  • Liver test abnormalities
  • Rashes
  • Urticaria
  • Pruritus
  • Taste disturbances
  • Idiosyncratic and symptomatic hepatic injury
  • Liver failure
  • Serious skin reactions
  • Severe neutropenia
  • Thrombocytopenia
  • Angioedema
  • Allergic reactions
  • Malaise
  • Fatigue
  • Vomiting
  • Arthralgia
  • Myalgia
  • Hair loss

Pregnancy & Lactation

  • Use during pregnancy not recommended
  • Presence in breast milk
  • Foetal toxicity and fertility studies
  • Advice for nursing mothers

Precautions & Warnings

  • Rare cases of liver failure
  • Serious skin reactions
  • External use only for cream
  • Avoid contact with eyes for cream
  • Assessment of pre-existing liver disease
  • Hepatotoxicity
  • Pretreatment serum transaminase tests

Use in Special Populations

  • Safety and efficacy in pediatric patients
  • Use in the elderly

Overdose Effects

  • Limited clinical experience
  • Symptoms of overdose

Therapeutic Class

  • Other Antifungal preparations
  • Topical Antifungal preparations

Storage Conditions

  • Cool and dry storage
  • Protection from light

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